[Corrigendum] miR‑335 promotes ferroptosis by targeting ferritin heavy chain 1 in in vivo and in vitro models of Parkinson's disease. [PDF]
Li X+11 more
europepmc +1 more source
A case of gamma 3 heavy chain disease with vacuolated plasma cells: a clinical, immunological, and ultrastructural study. [PDF]
Walter Feremans, M Caudron, Claude Bieva
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This study uncovers STAT6‐driven pulmonary fibrosis (PF) via suppression of PRKN‐mediated airway epithelial mitophagy, triggering mitochondrial dysfunction and ferroptosis. Rifabutin is identified as a potent STAT6 inhibitor that effectively reverses fibrotic progression. These findings reveal the STAT6‐PRKN axis as a pathogenic regulator and provide a
Youjing Yang+7 more
wiley +1 more source
Uncommon Entities, Uncommon Challenges: A Review of Rare Plasma Cell Disorders. [PDF]
Hanbali A, Alamer A, Alhayli S.
europepmc +1 more source
Heavy Chain Disease of the µ (γM) Type: Report of the First Case [PDF]
FRANK A. FORTE+6 more
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Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai+5 more
wiley +1 more source
Conserved heavy/light contacts and germline preferences revealed by a large-scale analysis of natively paired human antibody sequences and structural data. [PDF]
Dudzic P+11 more
europepmc +1 more source
Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy
This review provides a systematic overview of peptide‐based biomaterials in tumor radiotherapy, covering their roles as both radiosensitizers and radiopharmaceuticals. Peptide‐based radiosensitizers are generally divided into three categories: peptides as direct radiosensitizers, peptides as carriers of radiosensitizers, and targeted‐peptide‐modified ...
Qian Wang, Xinhui Chu, Jianfeng Liu
wiley +1 more source
Where are the immunoglobulins? A review of non-secretory multiple myeloma. [PDF]
Toscano MP, Nakashima MO.
europepmc +1 more source
Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao+8 more
wiley +1 more source