Results 221 to 230 of about 634,218 (335)

Autonomous Self‐Evolving Research on Biomedical Data: The DREAM Paradigm

Advanced Science, EarlyView.
DREAM is a fully autonomous, self‐evolving biomedical research system capable of independently formulating scientific questions, performing analyses, and making new discoveries without human intervention. Validated in biomedical studies, DREAM significantly outperforms human scientists in research efficiency, accelerating scientific discovery and ...
Luojia Deng, Yijie Wu, Yongyong Ren, Hui Lu   +3 more
wiley   +1 more source

IgG Biomarkers in Multiple Sclerosis: Deciphering Their Puzzling Protein A Connection. [PDF]

Biomolecules
Apeltsin L, Yu X.
europepmc   +1 more source

Bioorthogonal Reaction of o‐Quinone with Furan‐2(3H)‐One for Site‐Selective Tyrosine Conjugation and Construction of Bispecific Antibody Complexes

Advanced Science, EarlyView.
A site‐selective, efficient, and mild tyrosine conjugation via tyrosinase oxidation and nucleophilic addition, allowing for site‐selective functionalization of peptides, recombinant proteins, and IgGs. Site‐selective mono‐functionalization of IgGs at Y296 enables the construction of immunoliposomes.
Hongfei Chen, Zhiyi Xu, Yishu Bao, Farshad Shiri, Dingdong Yuan, Yuke Hu, Biquan Li, Bin Zeng, Xiaojing Li, Hao Kong, Zikang Wang, Wilson Chun‐Yu Lau, Zhenyang Lin, Jiang Xia   +13 more
wiley   +1 more source

Comprehensive Proteomic Profiling of Exfoliation Glaucoma Via Mass Spectrometry Reveals SVEP1 as a Potential Biomarker. [PDF]

Invest Ophthalmol Vis Sci
Li J, Ma Y, Xie L, Zhuo K, He Y, Ma X, Zheng S, Guo S, Tang Y, Muhetaer G, Aizezi M, Zhang D, Wumaier A, Zhang X, Tang C, Wang W, Huang W, Gao X.   +17 more
europepmc   +1 more source

Gamma heavy chain disease: clinical aspects and characterization of a deleted, noncovalently linked gamma1 heavy chain dimer (BAZ) [PDF]

, 1977
GB Faguet, BP Barton, Smith Ll, FA Garver   +3 more
openalex   +1 more source

Virome and Experimental Analysis Reveal Tryptophan‐Like Dissolved Organic Matter Contributes to the Persistence of Plant Viruses in River Water

Advanced Science, EarlyView.
Tryptophan‐like dissolved organic matter (Try‐like DOM), a key component of organic matter in river ecosystems, demonstrates significant protective effects against plant viruses. The protective mechanism operates via a “swimming firewall” mode, whereby free Try‐like DOM attenuates ultraviolet (UV) radiation and scavenges reactive oxygen species ...
Yujie Wang, Ming Chen, Liu Yang, Jun Ma, Jian Tang, Shengjun Wu, Chi He, J. Paul Chen   +7 more
wiley   +1 more source

An expandable synthetic library of human paired antibody sequences. [PDF]

PLoS Comput Biol
Marinov TM, Wasdin PT, Jordaan G, Janke AK, Abu-Shmais AA, Georgiev IS.   +5 more
europepmc   +1 more source

A case of gamma 3 heavy chain disease with vacuolated plasma cells: a clinical, immunological, and ultrastructural study. [PDF]

, 1979
Walter Feremans, M Caudron, Claude Bieva
openalex   +1 more source

Structural Implications of β‐Cardiac Myosin Heavy Chain Mutations in Human Disease

The Anatomical Record, 2014
M. Colegrave, M. Peckham
semanticscholar   +1 more source

Leucine‐Rich Repeat‐Containing G Protein‐Coupled Receptor 6 Ameliorates Pressure Overload‐Induced Cardiac Hypertrophy by Regulating Cardiomyocyte Metabolic Reprogramming

Advanced Science, EarlyView.
LGR6 overexpression ameliorates cardiac hypertrophy by regulating metabolic reprogramming through USP4‐PPARα pathway. Abstract Metabolic reprogramming is a pivotal mechanism in the pathogenesis of pathological cardiac hypertrophy. Leucine‐rich repeat‐containing G protein‐coupled receptor 6 (Lgr6) has emerged as a significant player in cardiovascular ...
Mengmeng Zhao, Jianfang Liu, Shanshan Peng, Zihui Zheng, Siqi Liu, Jun Wan, Yao Xu, Menglong Wang   +7 more
wiley   +1 more source