Results 21 to 30 of about 285,431 (226)
BMC Nephrology, 2023 Background Light and heavy chain deposition disease (LHCDD) is a rare condition characterised by the deposition of immunoglobulin components in the kidneys.
Yuki Shimamoto +11 more
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Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B. [PDF]
PLoS ONE, 2016 Botulinum neurotoxins (BoNTs) are counted among the most toxic substances known and are responsible for human botulism, a life-threatening disease characterized by flaccid muscle paralysis that occurs naturally by food poisoning or colonization of the ...
Sebastian Miethe +13 more
doaj +1 more source
Medicines, 2023 Background: Monoclonal immunoglobulin deposition disease (MIDD) includes three entities: light chain deposition disease (LCDD), heavy chain deposition disease (HCDD) and light and heavy chain deposition disease (LHCDD).
José C. De La Flor +10 more
doaj +1 more source
Current application of neurofilaments in amyotrophic lateral sclerosis and future perspectives
Neural Regeneration Research, 2021 Motor neuron disease includes a heterogeneous group of relentless progressive neurological disorders defined and characterized by the degeneration of motor neurons.
Yuri Matteo Falzone +6 more
doaj +1 more source
Case Reports in Oncology, 2021 We present a case report of a 62-year-old male, treated for kappa light chain multiple myeloma with chemotherapy followed by autologous stem cell transplant (ASCT) in 2014. He has been in complete remission for 4 years.
Sowmya Thanikachalam +4 more
doaj +1 more source
Hypertension, renal failure, and edema in a 38-year-old man: light chain deposition disease; a case report and review of the literature [PDF]
Journal of Nephropathology, 2014 Background: Monoclonal immunoglobulin deposition disease (MIDD) is a rare disease, usually manifesting between the 5th and 6th decades of life but can also occur earlier. Characteristic feature of MIDD is a non-fibrillar, Congo red negative deposition of
Sarmad Said +4 more
doaj +1 more source
Gamma heavy chain disease [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2018 Gamma heavy chain disease (HCD) is a rare variant of HCD, a family of syndromes associated with or representing a B cell malignancy variant. The hallmark characteristic and the pathogenic mechanism of HCD is the synthesis of a mutant, misfolded immunoglobulin heavy chain (IgH) incapable of either reaching a quaternary conformation with the ...
Bianchi, Giada, Anderson, Kenneth C
openaire +3 more sources
BMC Nephrology, 2018 Background Immunoglobulin heavy-and-light-chain amyloidosis (AHL amyloidosis) is a newly established disease entity where both the immunoglobulin heavy-chain and light-chain compose amyloid fibrils. The immunoglobulins responsible for the amyloid fibrils
Shun Manabe +6 more
doaj +1 more source
Acquired cutis laxa associated with light and heavy chain deposition disease
Indian Dermatology Online Journal, 2018 Acquired cutis laxa (ACL) is a rare connective tissue disorder characterized by pendulous and coarsely wrinkled skin. There have been few cases of its association to monoclonal immunoglobulin deposition disease (MIDD), which constitutes the light chain ...
Reena A Majithia +3 more
doaj +1 more source
Are papers addressing certain diseases perceived where these diseases are prevalent? The proposal to use Twitter data as social-spatial sensors [PDF]
, 2020 We propose to use Twitter data as social-spatial sensors. This study deals with the question whether research papers on certain diseases are perceived by people in regions (worldwide) that are especially concerned by the diseases. Since (some) Twitter data contain location information, it is possible to spatially map the activity of Twitter users ...
arxiv +1 more source