Results 141 to 150 of about 87,769 (315)

The Advanced Petroleum-Based Fuels Program DECSE and APBF Overview [PDF]

open access: yes, 2000
The following topics are summarized: Role of fuel blends in controlling engine-out emissions; Effect of fuels and lubricants on emission control devices; and Effect of fuels and lubricants on vehicle emissions and ...

core  

Metodología de análisis y diseño de lechos de frenado Methodology for assessement and design of arrestor beds

open access: yesRevista Ingeniería de Construcción, 2007
En pendientes descendentes prolongadas, los vehículos pesados enfrentan el riesgo de corte de frenos. Para mitigar el potencial daño, existen sistemas que permiten que el vehículo salga de la calzada hacia un dispositivo de contención. El más empleado en
Tomás Echaveguren   +2 more
doaj  

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi   +12 more
wiley   +1 more source

Unlocking Strength‐Toughness Dilemma in High‐Entropy Borides by Intragranular Microstructural Reconstruction

open access: yesAdvanced Science, EarlyView.
An extreme non‐equilibrium process combining heavy direct current sintering and TiSi2 addition is used to construct intragranular energy dissipation units within high‐entropy boride ceramics to overcome the strength‐toughness trade‐off. The resulting ceramic demonstrates attractive mechanical properties with a flexural strength of 887 MPa and a ...
Yingjun Liu   +13 more
wiley   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

open access: yesAdvanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu   +12 more
wiley   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

Mapping Occupational Hazards with a Multi-sensor Network in a Heavy-Vehicle Manufacturing Facility. [PDF]

open access: yesAnn Work Expo Health, 2019
Zuidema C   +9 more
europepmc   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

Errata supplement for QUT thesis 'Heavy vehicle suspensions : testing and analysis' [PDF]

open access: yes, 2011
Errata supplement to QUT thesis: 'Heavy vehicle suspensions : testing and ...
Davis, Lloyd E.
core  

Erratum: Frequency of heavy vehicle traffic and association with DNA methylation at age 18 years in a subset of the Isle of Wight birth cohort. [PDF]

open access: yesEnviron Epigenet, 2019
Commodore A   +8 more
europepmc   +1 more source

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