Results 31 to 40 of about 413,120 (257)

Double-targeted liposomes coated with matrix metallopeptidase-2-responsive polypeptide nanogel for chemotherapy and enhanced immunotherapy against cervical cancer

Materials Today Bio
Immunotherapy is a cornerstone in cancer treatment, celebrated for its precision, ability to eliminate residual cancer cells, and potential to avert tumor recurrence. Nonetheless, its effectiveness is frequently undermined by the immunosuppressive milieu
Zhimin Bai, Yibo Yang, Zutong Cui, Wenming Liang, Xin Zhang, Zihan Zhang, Jianming Sun, Zhiwei Liu, Kun Li, Ming Shi, Jian Li   +10 more
doaj   +1 more source

Mixing efficacy and residence time distribution measurement in heavy water upgradation plant using radiotracer

Nuclear Engineering and Technology
To evaluate the efficiency of catalyst packing and to characterize the liquid phase flow dynamics in a heavy water distillation column, a series of residence time distribution (RTD) measurements were carried out using radiotracer.
Sunil Goswami, Saumyajeet Mukherjee, Sulabh Gupta, Jayashree Biswal, Rajesh Kumar, V.K. Sharma, Kalyan Bhanja, H.J. Pant, K.T. Shenoy   +8 more
doaj   +1 more source

Progress and Perspectives on Pyrite-Derived Materials Applied in Advanced Oxidation Processes for the Elimination of Emerging Contaminants from Wastewater

Molecules
Emerging contaminants (ECs) in wastewater threaten environmental and human health, while conventional methods often prove inadequate. This has driven increased concern among decision makers, justifying the need for innovative and effective treatment ...
Jannat Javed, Yuting Zhou, Saad Ullah, Tianjiu Gao, Caiyun Yang, Ying Han, Hao Wu   +6 more
doaj   +1 more source

Proof of Aerobically Autoxidized Self-Charge Concept Based on Single Catechol-Enriched Carbon Cathode Material

Nano-Micro Letters, 2023
Highlights An air-breathing chemical self-charge concept of oxygen-enriched carbon cathode. The oxygen-enriched carbon material with abundant catechol groups. Rapid air-oxidation chemical self-charge of catechol groups. Abstract The self-charging concept
Junyan Wang, Wanchun Guo, Kesong Tian, Xinta Li, Xinyu Wang, Panhua Li, Yu Zhang, Bosen Zhang, Biao Zhang, Shuhu Liu, Xueai Li, Zhaopeng Xu, Junjie Xu, Haiyan Wang, Yanglong Hou   +14 more
doaj   +1 more source

Imaging Sub-Cellular Methionine and Insulin Interplay in Triple Negative Breast Cancer Lipid Droplet Metabolism

Frontiers in Oncology, 2022
Triple negative breast cancer (TNBC) is a particularly aggressive cancer subtype that is difficult to diagnose due to its discriminating epidemiology and obscure metabolome. For the first time, 3D spatial and chemometric analyses uncover the unique lipid
Anthony A. Fung, Khang Hoang, Honghao Zha, Derek Chen, Wenxu Zhang, Lingyan Shi   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Defective Ultrathin ZnIn2S4 for Photoreductive Deuteration of Carbonyls Using D2O as the Deuterium Source

Advanced Science, 2022
Deuterium (D) labeling is of great value in organic synthesis, pharmaceutical industry, and materials science. However, the state‐of‐the‐art deuteration methods generally require noble metal catalysts, expensive deuterium sources, or harsh reaction ...
Chuang Han, Guanqun Han, Shukai Yao, Lan Yuan, Xingwu Liu, Zhi Cao, Arun Mannodi‐Kanakkithodi, Yujie Sun   +7 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Revealing the Hemispherical Shielding Effect of SiO₂@Ag Composite Nanospheres to Improve the Surface Enhanced Raman Scattering Performance

Nanomaterials, 2021
Many studies widely used SiO2@Ag composite nanospheres for surface enhanced Raman scattering (SERS), which mainly contributes to electromagnetic enhancement.
Fengyan Wang, Daxue Du, Shan Liu, Linna Wang, Tifeng Jiao, Zhaopeng Xu, Haiyan Wang   +6 more
doaj   +1 more source