Results 51 to 60 of about 417,382 (265)
Simulation and modelling of heavy metals and water quality parameters in the river [PDF]
, 2022 Maryam Khalilzadeh Poshtegal +1 more
openalex +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
MoleculesChromium-containing wastewater poses severe threats to ecosystems and human health due to the high toxicity of hexavalent chromium (Cr(VI)). Although iron oxide nanoparticles (IONPs) show promise for Cr(VI) removal, their practical application is ...
Yu Gao +5 more
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Study on Hydrogen Embrittlement Behavior in Heat-Affected Zone of X80 Welded Pipe
MetalsHydrogen, as a clean energy source, has gradually become an important choice for the energy transformation in the world. Utilizing existing natural gas pipelines for hydrogen-blended transportation is one of the most economical and effective ways to ...
Lei Tang +8 more
doaj +1 more source
PHENOMENON OF LIGHT WATER IN PRODUCTS FOR ELDER PEOPLE
Вестник Северо-Кавказского федерального университета, 2022 Water belongs to the most important substance of all living organisms. Urbanization of society contributed to a significant increase in consumption of drinking and technical water and an increase in the amount of contaminated wastewater.
Mariya Gladkova +3 more
doaj
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Hemoglobin synthesis rates in young trained and untrained males and females are not different
Physiological ReportsWe employed deuterated water (2H2O) to compare the fractional synthetic rate (FSR) of hemoglobin in trained (n = 10) and untrained humans (n = 10). Participants had a mean V̇O2max of 49.8 [SD: 10.9] mL/kg/min, hemoglobin mass of 775 [180] g, and red ...
Hilkka Kontro +2 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source