KDM4B/DHX9 promotes chemoresistance in small-cell lung cancer through the MYCN-driven signaling pathway. [PDF]
Lyu Q +10 more
europepmc +1 more source
Inflammation and mechanical force‐induced bone remodeling
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon +6 more
wiley +1 more source
Signaling pathway mechanisms in pancreatic ductal adenocarcinoma tumor microenvironment and emerging targeting strategies for improved prognosis. [PDF]
Akinsipe T +7 more
europepmc +1 more source
Understanding exosomes in regenerative dentistry
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source
Site-Specific Abiraterone Protein-Drug Conjugates via Hedgehog Autoprocessing. [PDF]
Gulzar A +8 more
europepmc +1 more source
Understanding Exosomes in Hair Regeneration
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad +3 more
wiley +1 more source
Growth plate cartilage-targeting nanoparticles for pharmacological treatment of hypochondroplasia. [PDF]
Ye SH +14 more
europepmc +1 more source
Abstract Mushrooms are a ubiquitous and essential component in our biological environment and have been of interest to humans around the globe for millennia. Knowledge about mushrooms represents a prime example of cumulative culture, one of the key processes in human evolution.
Andrea Bender, Åge Oterhals
wiley +1 more source
Gli3R-mediated inhibition of hedgehog signaling alters the embryonic transcriptome in zebrafish. [PDF]
Moyer AJ, Thyme SB.
europepmc +1 more source
Cytologic Characteristics of the Feline Ovary at Different Sexual Stages
ABSTRACT Background Cytology is a valuable diagnostic tool in veterinary medicine, allowing rapid and minimally invasive diagnosis. However, its application in the reproductive tracts of small animals is limited, primarily used to assess mammary masses and stage the estrous cycle.
Alba Martí +4 more
wiley +1 more source

