Results 131 to 140 of about 3,054 (263)

RORα Coordinates Reciprocal Signaling in Cerebellar Development through Sonic hedgehog and Calcium-Dependent Pathways

, 2003
David Gold, Sung Hee Baek, Nicholas J. Schork, David W. Rose, DeLaine D. Larsen, Benjamin D. Sachs, Michael G. Rosenfeld, Bruce A. Hamilton   +7 more
openalex   +1 more source

Mutations in BMP4 Cause Eye, Brain, and Digit Developmental Anomalies: Overlap between the BMP4 and Hedgehog Signaling Pathways [PDF]

, 2008
Preeti Bakrania, Maria Efthymiou, Johannes Klein, Alison Salt, David J. Bunyan, Alex Wyatt, Chris P. Ponting, Angela Martin, Steven E. Williams, Victoria Lindley, Joanne Gilmore, Marie Restori, Anthony G. Robson, M. Neveu, Graham E. Holder, J. R. O. Collin, David Robinson, Peter Farndon, Heidi Johansen‐Berg, Dianne Gerrelli, Nicola Ragge   +20 more
openalex   +1 more source

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

Regulation and function of the sonic hedgehog (Shh) signal transduction pathway in isolated gastric parietal cells

, 2003
Vinzenz Stepan, Saravanan Ramamoorthy, H. Nitsche, Jung Park, Andrea Todisco   +4 more
openalex   +1 more source

Antbears and underground melons: A highly specialized seed dispersal mutualism mediated by scent

PLANTS, PEOPLE, PLANET, EarlyView.
Seed dispersal is critical for the establishment and persistence of populations of most plant species. We investigated the seed dispersal biology of an African melon, Cucumis humifructus, which is closely related to cultivated cucumbers and watermelons but differs in that it buries its fruits deep underground.
Steven D. Johnson, Anka Eichhoff, Jeremy J. Midgley   +2 more
wiley   +1 more source

The acetylation GLI1 affects arsenical-induced renal fibrosis by mediating the Hedgehog signalling pathway

Ecotoxicology and Environmental Safety
Arsenic exposure by drinking water is a key challenge in the field of public health worldwide. Research has found a connection between arsenic exposure and renal fibrosis, yet the mechanisms behind this are still unclear. In this study, rats were exposed
Pinya Liu, Yating Wang, Peiyu Jin, Qing Zhou, Liang Pei, Shuhua Xi   +5 more
doaj  

Epidermal Growth Factor Receptor Signaling Synergizes with Hedgehog/GLI in Oncogenic Transformation via Activation of the MEK/ERK/JUN Pathway [PDF]

, 2009
Harald Schnidar, Markus Eberl, Stefan Klingler, Doris Mangelberger, Maria Kasper, Cornelia Hauser‐Kronberger, Gerhard Regl, Renate Kroismayr, Richard Moriggl, Maria Sibilia, Fritz Aberger   +10 more
openalex   +1 more source

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

Small Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai, Jiawen Wang, Zihuan Lin, Danni Yu, Hui Yang, Jinsong Wei, Xiaoyu Li, Hao Hu, Chao Ni, Bing Zhao   +9 more
wiley   +1 more source

Indian hedgehog signaling pathway: Expression and regulation in pancreatic cancer

, 2004
Hany Kayed, Jörg Kleeff, Shereen Keleg, Junchau Guo, Knut Ketterer, Pascal O. Berberat, Nathalia A. Giese, Iréne Esposito, Thomas Giese, Markus W. Büchler, Helmut Frieß   +10 more
openalex   +1 more source

The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth [PDF]

, 2009
Valérian Dormoy, Sabrina Danilin, Véronique Lindner, Lionel Thomas, Sylvie Rothhut, Catherine Coquard, Jean‐Jacques Helwig, Didier Jacqmin, Hervé Lang, Thierry Massfelder   +9 more
openalex   +1 more source