Results 161 to 170 of about 20,915 (244)

Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis

, 2021
Bailey A. Allard, Wei Wang, Tana S. Pottorf, Hammad Mumtaz, Brittany Jack, Henry H. Wang, Luciane M. Silva, Damon T. Jacobs, Jinxi Wang, Erin E. Bumann, Pamela V. Tran   +10 more
openalex   +2 more sources

Targeting SPP1‐CD44‐Hedgehog Axis Elicits Therapeutic Effects in Hepatocellular Carcinoma by Suppressing Intratumoral Fibrosis

Cancer Science, EarlyView.
SPP1 was identified as a key driver of intratumoral fibrosis and hepatocellular carcinoma (HCC) progression through transcriptomic, histological, and functional analyses. Mechanistically, SPP1 promotes HSC activation and fibrosis via the SPP1–CD44–GLI1 axis, and pharmacologic inhibition of Hedgehog signaling effectively reduces tumor growth and ...
Atsushi Nara, Shu Shimada, Yoshimitsu Akiyama, Megumi Hatano, Yusuke Chino, Suguru Miyazawa, Hanako Tamura, Daisuke Asano, Yoshiya Ishikawa, Hiroki Ueda, Shuichi Watanabe, Eriko Katsuta, Keiichi Akahoshi, Kenichi Ohashi, Minoru Tanabe, Daisuke Ban, Shinji Tanaka   +16 more
wiley   +1 more source

Insight into tick and flea species infesting the North African Hedgehog <i>Atelerix algirus</i> in Tunisia. [PDF]

Int J Parasitol Parasites Wildl
Balti G, Aounallah H, Ouni A, Derghal M, Rhim A, Chemkhi J, Guizani I, Bouattour A, Guerbouj S, M'ghirbi Y.   +9 more
europepmc   +1 more source

Reviewer #2 (Public Review): Two-way Dispatched function in Sonic hedgehog shedding and transfer to high-density lipoproteins

openalex   +1 more source

Molecular Landscape in Limb Anomalies: Diagnostic Yield and New Candidate Genes

Clinical Genetics, EarlyView.
In 132 individuals with limb anomalies, diagnostic yield was 36% (47/132), including 25 novel variants, three cases with new phenotypes, and two candidate loci, HOXA11 and a small 2q31.1 deletion. Mouse data and exome‐wide analysis, key in identifying the candidate loci, represent an important opportunity for gene discovery.
Akram Mokhtari, Jade Charbonneau, Valancy Miranda, Khadijé Jizi, Marie‐Ange Delrue, Patricia Egerszegi, Isabelle Thiffault, Philippe M. Campeau   +7 more
wiley   +1 more source

Antimicrobial-Resistant <i>Staphylococcus</i> spp. Harbored by Hedgehogs (<i>Erinaceus europaeus</i>) in Central Italy. [PDF]

Antibiotics (Basel)
Bertelloni F, Pauselli F, Cagnoli G, Biscontri R, Ceccherelli R, Ebani VV.   +5 more
europepmc   +1 more source

Some aspects of the ecology of the hedgehog (Erinaceus europaeus L.) in the Manawatu, New Zealand: a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Zoology at Massey University

, 1972
John Parkes
openalex   +1 more source

Suppressing Wnt Signaling by the Hedgehog Pathway through sFRP-1

, 2006
Jing He, Tao Sheng, Arwen A. Stelter, Chengxin Li, Xiaoli Zhang, Mala Sinha, Bruce A. Luxon, Jingwu Xie   +7 more
openalex   +1 more source

Endocrine Resistance Score Based on Three Key Genes Predicts Prognosis and Reveals Potential Therapeutic Targets for ER+HER2− Breast Cancer

Cell Proliferation, EarlyView.
We generated endocrine‐resistant BC cell lines and identified CLEC3A, PCDH10, and ST3GAL1 as key endocrine‐resistant genes. More importantly, we validated their role in mediating resistance through PI3K‐AKT signalling and developed a predictive ERS with strong clinical relevance.
Liqin Ping, Lewei Zhu, Nian Chen, Xikun Liu, Jirui Zhong, Xiaoqing Sun, Hailin Tang, Kaiming Zhang   +7 more
wiley   +1 more source

Endoparasites of European hedgehogs (Erinaceus europaeus) in Germany and their zoonotic potential: proposed Capillaria ovoreticulata genetically identified as Capillaria putorii. [PDF]

Parasit Vectors
Schütte K, Springer A, Brandes F, Reuschel M, Fehr M, Kern A, Strube C.   +6 more
europepmc   +1 more source