Results 31 to 40 of about 276,693 (256)

Development of an Electronic Tool to Assess Patient Preferences in Geriatric Polypharmacy (PolyPref)

Patient Preference and Adherence, 2022
Annette Eidam,1 Anja Roth,1 Eduard Frick,2 Michael Metzner,2 Anette Lampert,2,3 Hanna M Seidling,2,3 Walter E Haefeli,2,3 Jürgen M Bauer1,4 1Center for Geriatric Medicine, Heidelberg University, AGAPLESION Bethanien Hospital Heidelberg, Heidelberg ...
Eidam A, Roth A, Frick E, Metzner M, Lampert A, Seidling HM, Haefeli WE, Bauer JM   +7 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Characterization of a Multidrug-Resistant Salmonella enterica Serovar Heidelberg Outbreak Strain in Commercial Turkeys: Colonization, Transmission, and Host Transcriptional Response

Frontiers in Veterinary Science, 2017
In recent years, multidrug-resistant (MDR) Salmonella enterica serovar Heidelberg (S. Heidelberg) has been associated with numerous human foodborne illness outbreaks due to consumption of poultry. For example, in 2011, an MDR S.
Bradley L. Bearson, Shawn M. D. Bearson, Torey Looft, Guohong Cai, Daniel C. Shippy   +4 more
doaj   +1 more source

Heidelberg

, 2012
Source: Felix Dahn: Gesammelte Werke. Erzählende und poetische Schriften, Zweite Reihe, Band 5: Gedichte und Balladen (Auswahl), Leipzig: Breitkopf und Härtel, 1912.
Volker Hartmann, Wilhelm Kühlmann
openaire   +3 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Percutaneous Endoscopic Gastrostomy Tube Placement in Patients with Head and Neck Cancer Treated with Radiotherapy

Cancer Management and Research, 2020
Kristin Lang, 1– 3 Rami A ElShafie, 1– 3 Sati Akbaba, 1– 3 Ronald Koschny, 4 Nina Bougatf, 1– 3, 5 Denise Bernhardt, 1– 3, 5 Stefan E Welte, 1– 3, 5 Sebastian Adeberg, 1– 3, 5 Matthias Hä ...
Lang K, ElShafie RA, Akbaba S, Koschny R, Bougatf N, Bernhardt D, Welte SE, Adeberg S, Häfner M, Kargus S, Plinkert PK, Debus J, Rieken S   +12 more
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Learning from Negative Space

Artivate, 2019
From its inception in 1965, the National Endowment for the Arts (NEA) has counted on its agency leaders to operate as policy entrepreneurs – working to influence the federal public policy process and advocating for increased public arts funding ...
Brea Heidelberg
doaj  

Effect of trans-cinnamaldehyde and peracetic acid alone or in combination on multidrug-resistant Salmonella Heidelberg on broiler drumsticks under scalding alone or with chilling and storage in sequence

Journal of Applied Poultry Research
Summary: This study determined the antibacterial effect of trans-cinnamaldehyde (TC), peracetic acid (PAA), and their combination against Salmonella Heidelberg on broiler drumsticks at scalding conditions alone or with chilling and storage in sequence ...
C. Peichel, D.V.T. Nair, S. Manjankattil, K.M. Reed, R.B. Cox, A.M. Donoghue, A. Kollanoor Johny   +6 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source