5-(carbamoylmethylene)-oxazolidin-2-ones as a promising class of heterocycles inducing apoptosis triggered by increased ROS levels and mitochondrial dysfunction in breast and cervical cancer [PDF]
, 2020 Oxazolidinones are antibiotics that inhibit protein synthesis by binding the 50S ribosomal subunit. Recently, numerous worldwide researches focused on their properties and possible involvement in cancer therapy have been conducted.
Armentano, B +10 more
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Calcium signalling links MYC to NUAK1 [PDF]
, 2018 NUAK1 is a member of the AMPK-related family of kinases. Recent evidence suggests that NUAK1 is an important regulator of cell adhesion and migration, cellular and organismal metabolism, and regulation of TAU stability.
Hedley, A, +5 more
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Delayed kinetics of poliovirus RNA synthesis in a human cell line with reduced levels of hnRNP C proteins. [PDF]
, 2010 The hnRNP C heterotetramer [(C1(3))C2] binds RNA polymerase II transcripts in the nucleus, along with other proteins of the core hnRNP complex, and plays an important role in mRNA biogenesis and transport.
Brunner, Jo Ellen +3 more
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Traditional Chinese medicine herbal mixture LQ arrests FUCCI-expressing HeLa cells in G₀/G₁ phase in 2D plastic, 2.5D Matrigel, and 3D Gelfoam culture visualized with FUCCI imaging. [PDF]
, 2015 We used the fluorescence ubiquitination-based cell cycle indicator (FUCCI) to monitor cell cycle arrest after treatment of FUCCI-expressing HeLa cells (FUCCI-HeLa) with a traditional Chinese medicine (TCM) herbal mixture LQ, previously shown to have anti-
Bouvet, Michael +4 more
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Ribosomal Proteins of HeLa Cells [PDF]
European Journal of Biochemistry, 1978 Ribosomal proteins from HeLa cells were analyzed by two‐dimensional polyacrylamide gel electrophoresis (Kaltschmidt–Wittmann) and dodecylsulfate polyacrylamide gel electrophoresis (Laemmli). 35 proteins are associated with the small ribosomal subunit and 47 proteins with the large ribosomal subunit.
Dietmar Schiffmann, Ivan Horak
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Protein clustering in chemically stressed HeLa cells studied by infrared nanospectroscopy [PDF]
, 2016 Photo-Thermal Induced Resonance (PTIR) nanospectroscopy, tuned towards amide-I absorption, was used to study the distribution of proteic material in 34 different HeLa cells, of which 18 were chemically stressed by oxidative stress with Na3AsO3.
BALDASSARRE, Leonetta +6 more
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Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. [PDF]
, 2016 Cellular amino acid uptake is critical for mTOR complex 1 (mTORC1) activation and cell proliferation. However, the regulation of amino acid uptake is not well-understood.
Braas, Daniel +4 more
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Electrolyte Metabolism in HeLa Cells [PDF]
The Journal of General Physiology, 1963 Methods have been developed to study cellular Na, K, and Cl concentrations in HeLa cells. Cell [Na] and [K] are functions of the age of the culture. As the culture grows [K], expressed in mmols/liter cell H2O, rises from an initial value of 121 to a peak of 206 at about 4 days, and thereafter falls until it has almost returned to the initial value by ...
A. K. Solomon, Margaret Wickson-ginzburg
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Bod1, a novel kinetochore protein required for chromosome biorientation [PDF]
, 2007 We have combined the proteomic analysis of Xenopus laevis in vitro–assembled chromosomes with RNA interference and live cell imaging in HeLa cells to identify novel factors required for proper chromosome segregation. The first of these is Bod1, a protein
Andersen, Jens S. +7 more
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EFFECT OF DACTYLARIN ON HELA CELLS
The Journal of Antibiotics, 1974 Dactylarin is a new antiprotozoal antibiotic which also exhibits cytotoxic activity. The decrease of mitotic index in treated HeLa cells indicates that the antibiotic inhibition is expressed prior to mitosis. Dactyiarin inhibited the progression or G2 cells into mitosis.
P. Nemec +3 more
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