Results 231 to 240 of about 391,392 (354)

Correlation between adherence to HeLa cells and serogroups, serotypes, and bioserotypes of Escherichia coli [PDF]

open access: bronze, 1985
Isabel C. A. Scaletsky   +5 more
openalex   +1 more source

Real‐Time, Label‐Free Classification of Cell Death Pathways via Holotomography‐Based Deep Learning Framework

open access: yesAdvanced Intelligent Systems, EarlyView.
A 3D holotomography system coupled with a deep learning model distinguishes how cells die—apoptosis, necroptosis or necrosis—without any fluorescent labels. Training on refractive index maps of HeLa cells yields 97% accuracy and flags necroptosis hours before chemical dyes.
Minwook Kim   +8 more
wiley   +1 more source

Adefovir anticancer potential: Network pharmacology, anti-proliferative and apoptotic effects in HeLa cells. [PDF]

open access: yesBiomol Biomed
Mateen Azhar M   +11 more
europepmc   +1 more source

Rod‐Like PLGA Microrobots with Enhanced Motion and Biodegradation for Magnetic‐Guided Drug Delivery

open access: yesAdvanced Intelligent Systems, EarlyView.
This study presents drug‐loaded Poly (lactic‐co‐glycolic acid) (PLGA) microrobots fabricated from an oil‐in‐water (O/W) emulsion of PLGA, Fe3O4 nanoparticles, and Adriamycin (DOX). They are formed by film‐forming and stretching microrobots, and exhibit motion analyzed via video‐snapshots, speed graphs, and shape changes, advancing targeted for drug ...
Junkai Zhang   +6 more
wiley   +1 more source

A Noncovalent Click‐to‐Release Strategy to Control Bond Cleavage and Prodrug Activation

open access: yesAngewandte Chemie, EarlyView.
Extending the click‐to‐release concept beyond covalent ligation, we introduce a noncovalent click‐to‐release strategy based on cucurbituril‐adamantane (CB‐Ad) association. A supramolecular preassembly encapsulating a self‐immolative guest (SIG) is rationally designed to prevent premature release, while adding a high‐affinity Ad guest initiates the CB ...
Xuancheng Fu   +9 more
wiley   +2 more sources

Long‐Read Genome Sequencing Establishes Biallelic Pathogenic Variants in DNM1 With Distinct Functional Effects as the Cause of Early Infantile Developmental and Epileptic Encephalopathy

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous de novo and inherited biallelic pathogenic variants in DNM1 have been reported in association with autosomal dominant (AD) and autosomal recessive (AR) developmental and epileptic encephalopathy, respectively, due to aberrant dynamin function or expression, with each inheritance pattern associated with a different mechanism of ...
Andy Drackley   +7 more
wiley   +1 more source

A Nonviral Neo‐Nucleocapsid for Cell‐Specific RNA Delivery Developed by Pseudo‐Cyclic Peptide Grafting and Directed Evolution

open access: yesAngewandte Chemie, EarlyView.
Nonviral neo‐nucleocapsids developed from a repurposed bacterial protein cage, and macrocyclic peptide pharmacophores via protein‐protein ligation, bacteria‐based directed evolution, lasso‐grafting, and mammalian cell‐based directed evolution enabled cell specific RNA delivery.
Daiki Kanayama   +4 more
wiley   +2 more sources

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