Results 241 to 250 of about 391,392 (354)

Quantitative proteomic data of flotillin-2 interactome within detergent resistant membranes of HeLa cells. [PDF]

open access: yesData Brief
Hryniewicz-Jankowska A   +5 more
europepmc   +1 more source

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

open access: yesAdvanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna   +9 more
wiley   +1 more source

Adhesive Photoinitiator Constructs Polymer Jackets on Enzymes: Direct, Release‐Free Cytosolic Delivery

open access: yesAngewandte Chemie, EarlyView.
A supramolecular adhesive photoinitiator, GuCD⊃BP‐SH, overcomes a central dilemma in enzyme therapeutics. The initiator, featuring a guanidinium‐modified cyclodextrin (GuCD) host, triggers formation of a semi‐permeable polymer jacket directly on an enzyme.
Shuran He, Soumen Ghosh, Kou Okuro
wiley   +2 more sources

Baicalein induces apoptosis of human cervical cancer HeLa cells in vitro

open access: bronze, 2014
Yong Peng   +6 more
openalex   +2 more sources

Thiosulfonate‐Derived BODIPY “Stick and Glue” Strategy for Fluorescent Thiol Labeling

open access: yesAngewandte Chemie, EarlyView.
We present a powerful photochemical strategy for converting disulfide bonds into stable thioether linkages via a [1,2]‐sigmatropic rearrangement. By integrating this reaction into traditional methanethiosulfonate‐based thiol labeling, we enable light‐triggered stabilization of peptide and protein conjugates with enhanced robustness and versatility ...
Lucie Šálková   +4 more
wiley   +1 more source

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