Results 51 to 60 of about 1,312 (280)

Research on Lateral Bearing Behavior of Spliced Helical Piles with the SPH Method

open access: yesApplied Sciences, 2022
The length of a spliced pile is 2 m assembled from an original spiral pile using a connector. The whole pile is the structure of the upper straight pipe and the lower spiral.
Guofeng Ren   +6 more
doaj   +1 more source

STUDY ON PENETRATION MECHANISM OF SCREW PILE BASED ON SOIL MOVEMENT AROUND HELICAL WING

open access: yes, 2007
application/pdfModel tests were conducted to observe the soil movement around helical wing, in order to investigate the penetration mechanism of screw pile.
中沢, 楓太   +8 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

A Machine Learning-Based Approach for Predicting Installation Torque of Helical Piles from SPT Data

open access: yesBuildings
Helical piles are advantageous alternatives in constructions subjected to high tractions in their foundations, like transmission towers. Installation torque is a key parameter to define installation equipment and the final depth of the helical pile. This
Marcelo Saraiva Peres   +2 more
doaj   +1 more source

Helical pile installation for offshore renewable energy exploration in clay seabed

open access: yes, 2022
Offshore wind and wave energy exploration are moving from shallow waters with fixed foundations to deep waters with floating devices. Helical pile has the potential to be used as both shallow water foundations and deep water anchors due to its ‘quiet ...
Shah Neyamat Ullah (9841577)   +2 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Settlement based load capacity curve for single helix helical pile in c - ϕ soil

open access: yesSoils and Foundations, 2023
Helical piles are getting increasingly popular for lightweight engineering applications. Currently, the helical pile is mostly designed with torque capacity; however, it cannot explain the foundation's anticipated settlement.
Nur Mohammad Shuman   +2 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Laboratory Model Study on the Pile-Forming Mechanisms and Bearing Deformation Characteristics of CFA Piles

open access: yesAdvances in Civil Engineering, 2021
To study the pile-forming mechanism and bearing deformation characteristics of continuous flight auger (CFA) piles, a series of procedures, including helical drilling, pulling up/grouting, and inserting cage/pile forming, were simulated in clay-sand ...
Deliang Zhu   +4 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

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