Results 181 to 190 of about 194,742 (384)
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.ABSTRACT Vertebrate growth rates may respond to maternally supplied steroids, yet injections of individual hormones into avian eggs of different species have produced inconsistent results. This might be because diverse steroids' concentrations are naturally correlated in yolks, injections are not elevating hormones at critical times in development, or ...
S. K. Winnicki +4 more
wiley +1 more source
New Plant Protection, EarlyView.The striped flea beetle, Phyllotreta striolata, is a globally notorious pest of cruciferous vegetables. In this study, we successfully sequenced the whole genome of the Chinese population of P. striolata. Comparative analysis with the reference genome of the Canadian population enabled a high‐resolution examination of genetic variation, which is ...
Kui Wang +3 more
wiley +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
PROTEOMICS, EarlyView.ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Analysis of mitotic and meiotic defects in Saccharomyces cerevisiae SRS2 DNA helicase mutants. [PDF]
, 1992 Francesca Palladino, Hannah L. Klein
openalex +1 more source
Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery
PROTEOMICS, EarlyView.ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam +12 more
wiley +1 more source
Case Studies of Orphan Domain Reclassification in ECOD by Expert Curation
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Homology‐based protein domain classification is a powerful tool for gaining biological insights into protein function. This classification process has been significantly enhanced by the availability of experimental structures and high‐accuracy structural models generated by advanced tools such as AlphaFold.
Jimin Pei +3 more
wiley +1 more source
Helicases at Work: The Importance of Nucleic Acids Unwinding Under Cold Stress
DNASeparation of duplex strands of nucleic acids is a vital process in the nucleic acid metabolism and survival of all living organisms. Helicases are defined as enzymes that are intended to unwind the double-stranded nucleic acids.
Theetha L. Pavankumar +3 more
doaj +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The homo‐dimeric, ring‐shaped bacterial DNA sliding clamp, β‐clamp, is a central hub in DNA replication and repair. It interacts with a plethora of proteins via their short linear motifs, binding to the same hydrophobic binding pocket on β‐clamp. Although the structure, functions, and interactions of β‐clamp have been amply studied, less focus
Signe Simonsen +5 more
wiley +1 more source
Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins. [PDF]
, 1992 A Aboussekhra +3 more
openalex +1 more source