Results 191 to 200 of about 194,742 (384)
From Fluctuations to Function: Unveiling the Role of Stochasticity in Life‐Like Systems
In this short review, we put forward the idea that randomly fluctuating, or stochastic, molecular events can and do play a role in the emergence of complex biological phenomena at longer length scales. There is a growing body of evidence of this occurring in natural systems, and we survey the computational and experimental attempts of researchers to ...
Aleksa Lakic, Alexander F. Mason
wiley +1 more source
CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma+6 more
wiley +1 more source
Double helicase II (uvrD)-helicase IV (helD) deletion mutants are defective in the recombination pathways of Escherichia coli [PDF]
V M Mendonca+2 more
openalex +1 more source
Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36
Michael C. Chen+6 more
semanticscholar +1 more source
Characterization of the Helicase Activity of the Escherichia coli UvrAB Protein Complex
Euk Y. Oh, Lawrence I. Grossman
openalex +1 more source
The xeroderma pigmentosum group B protein ERCC3 produced in the baculovirus system exhibits DNA helicase activity [PDF]
Libin Ma+3 more
openalex +1 more source
▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding+5 more
wiley +1 more source