Results 211 to 220 of about 189,964 (332)

MAVISp: A modular structure‐based framework for protein variant effects

Protein Science, Volume 35, Issue 5, May 2026.
Abstract The role of genomic variants in disease has expanded significantly with the advent of advanced sequencing techniques. The rapid increase in identified genomic variants has led to many variants being classified as Variants of Uncertain Significance or as having conflicting evidence, posing challenges for their interpretation and ...
Matteo Arnaudi, Mattia Utichi, Kristine Degn, Matteo Tiberti, Ludovica Beltrame, Karolina Krzesińska, Pablo Sánchez‐Izquierdo Besora, Eleni Kiachaki, Simone Scrima, Laura Bauer, Katrine Meldgård, Anna Melidi, Lorenzo Favaro, Anu Oswal, Guglielmo Tedeschi, Terézia Dorčaková, Alberte Heering Estad, Joachim Breitenstein, Jordan Safer, Paraskevi Saridaki, Valentina Sora, Francesca Maselli, Philipp Becker, Jérémy Vinhas, Alberto Pettenella, Matteo Lambrughi, Claudia Cava, Anna Rohlin, Mef Nilbert, Sumaiya Iqbal, Peter Wad Sackett, Burcu Aykac Fas, Elena Papaleo   +32 more
wiley   +1 more source

RPA directly stimulates Mer3 helicase processivity to ensure normal crossover formation in meiosis. [PDF]

Nat Commun
Altmannova V, Orlić L, Carrasco C, Adam C, Aicart-Ramos C, Guerrini D, Janning P, Borde V, Matos J, Moreno-Herrero F, Weir JR.   +10 more
europepmc   +1 more source

DEAD-box helicase DDX24 is essential for endothelial mitochondrial function to maintain the blood-brain barrier

Shuai Li, Yuxuan Liu, Yingying Dong, Yujiao Gong, Simeng He, Jianyu Yuan, Shengfeng Deng, Qianqian Zhang, Lijie Wang, Fei Liu, Qiuyun Tu, Hong Shan, Huanhuan He   +12 more
openalex   +1 more source

The mRNA of DEAD Box Protein p72 Is Alternatively Translated into an 82-kDa RNA Helicase [PDF]

, 2002
Heike Uhlmann‐Schiffler, Oliver G. Rößler, H. Stahl   +2 more
openalex   +1 more source

Novel insights into the assembly of the yeast translation initiation multifactor complex: The critical role of eIF5

Protein Science, Volume 35, Issue 5, May 2026.
Abstract The eukaryotic translation initiation is a biological process in which at least a dozen eukaryotic initiation factors (eIFs) are involved. Specifically, eIF3, eIF1, eIF5, and eIF2 as a ternary complex (eIF2‐TC) bound to GTP and methionyl initiator tRNA (Met‐tRNAiMet).
Borja Sáez de la Fuente, Laura Villamayor‐Belinchón, José Rafael Ciges‐Tomas, Marisa López‐Redondo, Carolina Espinosa, Elisabetta Boeri Erba, José L. Llácer   +6 more
wiley   +1 more source

Structures of nucleotide-bound Redondovirus Rep protein link conformation and function. [PDF]

PLoS Pathog
Montermoso S, Gupta K, Pumroy RA, Moiseenkova-Bell V, Bushman FD, Van Duyne GD.   +5 more
europepmc   +1 more source

Family‐level specialization in protein domain insertion architectures

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Domain insertion creates architectures where one domain interrupts another's sequence. Analysis across 2.7 million classified domains reveals that insertions occur in 20% of multidomain proteins, with 331 families exhibiting consistent architectural roles: 162 function exclusively as hosts, while 169 exclusively serve as inserted modules, such
R. Dustin Schaeffer, Rui Guo, Jing Zhang, Qian Cong, Nick V. Grishin   +4 more
wiley   +1 more source

Nonequilibrium phases of a biomolecular condensate facilitated by enzyme activity.

Soft Matter
Coupe S, Fakhri N.
europepmc   +1 more source

Kinetic Characterization and Domain Analysis of the helicase RecD2 from Deinococcus radiodurans

, 2010
William R. Shadrick
openalex   +1 more source

Characterization of Recombinant Autographa californica Nuclear Polyhedrosis Virus (NPV) Expressing the β-Galactosidase Gene in both Sf21 and Bm5 Cells by Bombyx mori NPV p143 Helicase Gene

, 1997
Byung Rae Jin, Hyung Joo Yoon, Prabhakara V. Choudary, Seok Kwon Kang   +3 more
openalex   +1 more source