Results 221 to 230 of about 189,964 (332)

Advances in Avian Diagnostic Pathology: Current Trends, Challenges and Future Directions: A Review

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Advances in avian diagnostic pathology integrate histopathology, immunohistochemistry, molecular diagnostics and digital pathology to enhance the detection and management of poultry diseases. Emerging tools, including machine learning and artificial intelligence, further improve diagnostic accuracy, disease surveillance and outbreak prediction.
Gebyaw Menge Getnet   +2 more
wiley   +1 more source

Tho1 and MOS11 promote nucleic acid double-strand unwinding by facilitating DEAD-box helicase oligomerization. [PDF]

open access: yesNucleic Acids Res
Becker F   +6 more
europepmc   +1 more source

Multi‐Omics Signatures of Organ Clocks in Biological Aging and Disease: A Conceptual Framework for Organ‐Specific Aging Clocks

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Organ‐specific aging clocks integrating genomics, epigenomics, transcriptomics, proteomics, and metabolomics offer a more accurate assessment of biological aging than single‐omics approaches. This review proposes a multi‐omics framework emphasizing tissue data, longitudinal study designs, and clinically meaningful training outcomes to advance the ...
Maria Vasileiou   +3 more
wiley   +1 more source

Structural insights into WRN helicase reveal conformational states and opportunities for MSI-H cancer drug discovery. [PDF]

open access: yesCommun Biol
Fletcher CT   +12 more
europepmc   +1 more source

Integrated 2D–3D Proteomic Profiling Identifies MLK4 as a Microenvironment‐Responsive Regulator of Chemotherapeutic Resistance in Human Glioblastoma Cells

open access: yesBiology of the Cell, Volume 118, Issue 5, May 2026.
Glioblastoma U251MG cells were cultured in 2D monolayers and 3D spheroids to model tumor architecture. Comparative LC–MS/MS proteomics identified proteins associated with chemoresistance in 3D conditions. Selected candidates were functionally validated by gene knockdown and drug sensitivity assays to confirm their roles in modulating glioblastoma ...
Wannawat Khotchawan   +6 more
wiley   +1 more source

Stalling the Enemy: Targeting Nsp13 for Next-Generation SARS-CoV-2 Antivirals. [PDF]

open access: yesInt J Mol Sci
Castro JM   +13 more
europepmc   +1 more source

The Role of Histone Modifications in Plant Priming and Their Analysis by Chromatin Immunoprecipitation

open access: yesPhysiologia Plantarum, Volume 178, Issue 3, May/June 2026.
ABSTRACT Plants are frequently exposed to adverse conditions. Priming, also known as acclimation or hardening, induces stress memory and prepares plants for future challenges by activating defense and protective mechanisms. For this reason, priming is an effective means to maintain plant yield in the face of climate change. Memory behind the priming is
Aslihan Temel, Nihal Gören‐Sağlam
wiley   +1 more source

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