Results 271 to 280 of about 168,391 (336)

The Stalk and 1B Domains Are Required for Porcine Deltacoronavirus Helicase NSP13 to Separate the Double-Stranded Nucleic Acids, and the Deletion of the ZBD Impairs This Activity. [PDF]

Animals (Basel)
Wu C, Tao L, Zhou Q, Zhang F, Zeng Y.
europepmc   +1 more source

Controlling Topology of a Telomeric G‐quadruplex DNA With a Chemical Cross‐link

Chemistry – A European Journal, Volume 31, Issue 40, July 17, 2025.
Thermodynamically stable G‐quadruplex (G4) DNA: Chemical cross‐linking between distant nucleotides led to formation of G4‐DNA that is stable in the presence of complementary DNA. This methodology can be used to reliably form G4s within DNA fibers for subsequent structural studies of G4‐protein interactions.
Bruce Chilton, Patrick J. B. Edwards, Geoffrey B. Jameson, Tracy K. Hale, Vyacheslav V. Filichev   +4 more
wiley   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, Volume 19, Issue 7, Page 1998-2013, July 2025.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Quinazoline Derivative kzl052 Suppresses Prostate Cancer by Targeting WRN Helicase to Stabilize DNA Replication Forks. [PDF]

Int J Mol Sci
Yu J, Yu G, Cheng S, Hu L, Zan N, Xu B, Cao Y, Luo H.   +7 more
europepmc   +1 more source

DDX3 Regulates the Cap‐Independent Translation of the Japanese Encephalitis Virus via Its Interactions with PABP1 and the Untranslated Regions of the Viral Genome

Advanced Science, Volume 12, Issue 27, July 17, 2025.
Japanese encephalitis virus (JEV) employs a cap‐independent (CI) translation strategy to evade host translational shutoff. During the shut‐off of host cellular canonical translation, DEAD‐box protein 3 (DDX3) bind to JEV UTRs to establish a closed‐loop architecture, and its interaction with poly(A)‐binding protein 1 (PABP1) to form DDX3/PABP1/eIF4G ...
Chenxi Li, Linjie Zhang, Chenyang Tang, Xuan Chen, Jing Shi, Qingyu Li, Xue Jiao, Jinyao Guo, Bin Wang, Kefan Bu, Abdul Wahaab, Yuguo Yuan, Ming‐an Sun, Yanhua Li   +13 more
wiley   +1 more source

Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair

, 1999
Karsten Theis
openalex   +2 more sources

Monitoring SARS-CoV-2 Nsp13 helicase binding activity using expanded genetic code techniques. [PDF]

RSC Chem Biol
Lundrigan E, Hum C, Ahmed N, Pezacki JP.
europepmc   +1 more source

Sequencing of the p143 gene encoding a putative DNA helicase of the Spodoptera exigua (Lepidoptera : Noctuidae) nucleopolyhedrovirus I1 isolate from Japan

, 1999
Tohru Yanase, Naoyuki Yonemura, Chisa Yasunaga, Takeshi Kawarabata   +3 more
openalex   +2 more sources

DEAD-box RNA helicase 10 inhibits porcine circovirus type 3 replication by interacting with the viral capsid protein and activating interferon responses. [PDF]

J Virol
Zhou J, Zhu N, Dai Q, Sun H, Zhao J, Qiu Y, Zhou B, Wang D, Cui Y, Guo J, Feng X, Hou L, Liu J.   +12 more
europepmc   +1 more source

Novel Quinazolinones Active against Multidrug‐Resistant Mycobacterium Tuberculosis: Synthesis, Antimicrobial Evaluation, and in Silico Exploration of Penicillin‐Binding Protein 1A as a Potential Target

ChemMedChem, Volume 20, Issue 13, July 1, 2025.
Quinazolinone‐based compounds emerge as potent antimycobacterial agents, showing low minimum inhibitory concentrations against drug‐resistant Mycobacterium tuberculosis. Molecular modeling uncovers a novel allosteric site in PonA1 targeted by these derivatives.
Marek Kerda, Daria Nawrot, Petr Šlechta, Miroslav Domanský, Asal Askari, Hanieh Kamangar, Ondřej Janďourek, Klára Konečná, Pavla Paterová, Ingrid Hlbočanová, Miloslav Macháček, Matteo Mori, Fiorella Meneghetti, Martin Doležal, Jan Zitko, Ghada Bouz   +15 more
wiley   +1 more source