Spatiotemporal control in biomedicine: photoswitchable peptides and foldamers
Photopharmacology integrates light‐based technology with pharmacology to achieve precise control over biological processes, offering non‐invasive activation and spatiotemporal regulation of biomolecular activity. Within this field, photoswitchable peptides and foldamers provide a powerful approach in precision medicine, enabling reversible ...
Eszter Erdei+5 more
wiley +1 more source
Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH. [PDF]
Ishtiaq Qadri+4 more
openalex +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
SRS2 is required for MUS81-dependent CO formation in zmm mutants. [PDF]
Petiot V+3 more
europepmc +1 more source
The Interaction between Helicase and Primase Sets the Replication Fork Clock [PDF]
Killu Tougu, Kenneth J. Marians
openalex +1 more source
Liver‐specific lncRNAs associated with liver cancers
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina+3 more
wiley +1 more source
Functional investigation of the RNA helicase MOV10 with respect to its interplay with factors involved in nonsense-mediated mRNA decay. [PDF]
Xue G+7 more
europepmc +1 more source
Disruption of a topoisomerase-DNA cleavage complex by a DNA helicase.
M. T. Howard+3 more
openalex +2 more sources
Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies
[Color figure can be viewed at www.annalsofneurology.org] Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical ...
Brent L. Fogel+10 more
wiley +1 more source