Results 301 to 310 of about 194,742 (384)

The role of post-translational modifications in parvovirus life cycle. [PDF]

Front Vet Sci
Liu P, Yang L.
europepmc   +1 more source

Curcumin and Resveratrol as Dual Modulators of the STAT3 Pathway in Lung Cancer: A Comprehensive Review

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
The STAT3 pathway plays a crucial role in lung cancer by regulating cell proliferation, survival, angiogenesis, invasion, and metastasis. CUR and RES have emerged as potential therapeutic agents due to their ability to inhibit the STAT3 pathway, reducing tumor growth, angiogenesis, migration, and invasion.
Mohammad Yasin Zamanian, Klavdiya A. Turkadze, Mehraveh Sadeghi Ivraghi, Maryam Golmohammadi, Maryam Sharifi, Zahra Keshtpour Amlashi   +5 more
wiley   +1 more source

The YoaA-χ helicase modulates the dynamics of single-stranded DNA binding protein on DNA. [PDF]

Nat Commun
Weeks-Pollenz SJ, Petrides MJ, Padgett-Pagliai KA, Davis R, Harris KK, Bloom LB.   +5 more
europepmc   +1 more source

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes

Nature Structural &Molecular Biology, 2015
Inessa De, Sergey Bessonov, Romina V. Hofele, K. D. Santos, C. Will, H. Urlaub, R. Lührmann, V. Pena   +7 more
semanticscholar   +1 more source

The Serine Protease and RNA-Stimulated Nucleoside Triphosphatase and RNA Helicase Functional Domains of Dengue Virus Type 2 NS3 Converge within a Region of 20 Amino Acids

, 1999
Haitao Li, Stephen Clum, Shihyun You, K.E. Ebner, R. Padmanabhan   +4 more
openalex   +1 more source

Synthetic Lethal Combinations of DNA Repair Inhibitors and Genotoxic Agents to Target High‐Risk Diffuse Large B Cell Lymphoma

Hematological Oncology, Volume 43, Issue 5, September 2025.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most common hematological malignancy. More than half of DLBCL patients achieve long‐term remission after treatment, but a third relapse after conventional Rituximab (R)‐based chemotherapy regimens, such as CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone).
Sara Ovejero, Julie Devin, Laura Alibert, Camille Soun, Yea‐Lih Lin, Laure Dutrieux, Matthieu Abouladze, Elvira Garcia de Paco, Ouissem Karmous Gadacha, Angelos Constantinou, Guillaume Cartron, Charles Herbaux, Olivier Elemento, Philippe Pasero, Sandrine Roulland, Jérôme Moreaux, Caroline Bret   +16 more
wiley   +1 more source

DNA double-strand break end resection factors and WRN facilitate mitotic DNA synthesis in human cells. [PDF]

Nat Commun
Barwacz SA, Lundgaard K, Wu W, Richter PH, Ren L, Bhowmick R, Gonçalves Dinis MM, Kanemaki MT, Liu Y.   +8 more
europepmc   +1 more source

Mitochondrial Dysfunction in Neurodegenerative Diseases

MedComm, Volume 6, Issue 9, September 2025.
Overview of mitochondrial dysfunction in neurodegenerative diseases (NDDs). Mitochondrial dysfunction in NDDs involves impaired ATP synthesis, Ca2+ imbalance, oxidative stress, and apoptosis. Assessment methods integrate functional assays, omics, and imaging.
Chongyang Chen, Yujie Zhao, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Xifei Yang, Ming Lu, Gong‐Ping Liu   +10 more
wiley   +1 more source

RNA helicase DDX21 coordinates transcription and ribosomal RNA processing

Nature, 2014
Eliezer Calo, Ryan A. Flynn, Lance R. Martin, R. Spitale, Howard Y. Chang, J. Wysocka   +5 more
semanticscholar   +1 more source

Disruption of Spike Priming in Virus Entry: Tetrandrine as a Pan‐Coronavirus Inhibitor

MedComm, Volume 6, Issue 9, September 2025.
Tetrandrine inhibits the infection of HCoV‐OC43, HCoV‐229E, SARS‐CoV‐2, and its major variants by blocking virus entry. Specifically, tetrandrine breaks the interaction between TMPRSS2 and Spike, therefore suppress its priming and the following membrane fusion, and induces Spike to degradation.
Kun Wang, Huiqiang Wang, Shuo Wu, Ge Yang, Haiyan Yan, Lijun Qiao, Xingqiong Li, Mengyuan Wu, Jiandong Jiang, Yuhuan Li   +9 more
wiley   +1 more source