Results 311 to 320 of about 194,742 (384)

ATPase-dependent duplex nucleic acid unwinding by SARS-CoV-2 nsP13 relies on facile binding and translocation along single-stranded nucleic acid. [PDF]

J Biol Chem
Park J, Jeong YJ, Chauhan K, Koh HR, Kim DE.   +4 more
europepmc   +1 more source

Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase.

ACS Infectious Diseases, 2015
Noreena L. Sweeney, Alicia M. Hanson, S. Mukherjee, J. Ndjomou, B. Geiss, J. Jordan Steel, K. Frankowski, Kelin Li, F. Schoenen, D. Frick   +9 more
semanticscholar   +1 more source

Novel Findings in Pediatric and Adolescent Patients With Cancer and a Germline SMARCA4 Variant

Pediatric Blood &Cancer, Volume 72, Issue 9, September 2025.
ABSTRACT Introduction SMARCA4 is a known susceptibility gene for malignant rhabdoid tumors (MRT) in children and small cell carcinoma of the ovary hypercalcemic type (SCCOHT) in young females and women. Recently, a novel association between germline SMARCA4 variants and predisposition to neuroblastoma was proposed.
Nienke van Engelen, Ronald. R. de Krijger, Michelle M. Kleisman, Lennart. A. Kester, Saskia M. J. Hopman, Mariette E. G. Kranendonk, Marijn A. Vermeulen, Carli Tops, Seok‐Young Kim, Hans Clevers, Kornelia Neveling, Roland. P. Kuiper, Marjolijn C. J. Jongmans   +12 more
wiley   +1 more source

A four-in-one replicase integrating key enzymatic activities for DNA replication. [PDF]

Nucleic Acids Res
Zhang Y, Lu X, Zhu B, Huang F.
europepmc   +1 more source

Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures

Proceedings of the National Academy of Sciences of the United States of America, 2015
A. Pike, Shivasankari Gomathinayagam, Paolo Swuec, Matteo Berti, Ying Zhang, C. Schnecke, Francesca Marino, F. von Delft, L. Renault, Alessandro Costa, O. Gileadi, A. Vindigni   +11 more
semanticscholar   +1 more source

Machine learning‐driven GWAS uncovers novel candidate genes for resistance to frosty pod rot and witches' broom disease in cacao

The Plant Genome, Volume 18, Issue 3, September 2025.
Abstract Cacao (Theobroma cacao), the source of chocolate, is threatened by devastating diseases like frosty pod rot (FPR) and witches' broom disease (WBD), impacting global production and farmer livelihoods. Here, we employ a machine learning‐driven genome‐wide association study to dissect the genetic architecture of disease resistance and ...
Ezekiel Ahn, Sunchung Park, Insuck Baek, Dongho Lee, Jishnu Bhatt, Seunghyun Lim, Jae Hee Jang, Dapeng Zhang, Moon S. Kim, Lyndel W. Meinhardt   +9 more
wiley   +1 more source

Mechanisms of Viral DNA Replication of Human Papillomavirus: E2 Protein-Dependent Recruitment of E1 DNA Helicase to the Origin of DNA Replication. [PDF]

Int J Mol Sci
Rana A, Yilmaz G, Biswas-Fiss EE, Biswas S.   +3 more
europepmc   +1 more source

Chromosome‐level genome of Zoysia sinica in the intertidal zone reveals genomic insights into waterlogging stress adaptation

The Plant Genome, Volume 18, Issue 3, September 2025.
Abstract Zoysia sinica is a perennial grass that thrives in intertidal zones, even under extreme waterlogging stress. In this study, we present a high‐quality chromosome‐level genome assembly of Z. sinica, with a total size of 312.67 Mb. Through genome annotation, we identified 29,551 protein‐coding genes in the Z. sinica genome and re‐annotated 32,925,
Hyeonseon Park, Eunji Bae, Jae Gyeong Jung, Jaewook Kim, Bae Young Choi, Geungjoo Lee, Changsoo Kim, Donghwan Shim   +7 more
wiley   +1 more source

A back-up mechanism for replication. [PDF]

Elife
Charbon G, Løbner-Olesen A.
europepmc   +1 more source

Genetic mapping and haplotype analysis identify novel candidate genes for high night temperature tolerance in winter wheat

The Plant Genome, Volume 18, Issue 3, September 2025.
Abstract A diverse panel of 320 winter wheat (Triticum aestivum L.) genotypes was evaluated for yield‐related parameters under control and high night‐time temperature (HNT) stress using custom‐designed, movable field‐based heat tents over 2 years. Genome‐wide association mapping identified several significant single nucleotide polymorphisms (SNPs ...
Dinesh Kumar Saini, Nathan T. Hein, Impa Somayanda, Raju Bheemanahalli, Troy Ostmeyer, S. V. Krishna Jagadish   +5 more
wiley   +1 more source