Results 321 to 330 of about 194,742 (384)

DnaB and DciA: mechanisms of helicase loading and translocation on ssDNA. [PDF]

Nucleic Acids Res
Gao N, Mazzoletti D, Peng A, Olinares PDB, Morrone C, Garavaglia A, Gouda N, Tsoy S, Mendoza A, Chowdhury A, Cerullo A, Bhavsar H, Rossi F, Rizzi M, Chait BT, Miggiano R, Jeruzalmi D.   +16 more
europepmc   +1 more source

CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language [PDF]

, 2018
Fiala, Elise, Willing, Marcia
core   +1 more source

Dissecting the genomic regions, candidate genes and pathways using multi‐locus genome‐wide association study for stem rot disease resistance in groundnut

The Plant Genome, Volume 18, Issue 3, September 2025.
Abstract Stem rot, caused by Sclerotium rolfsii Sacc., is a devastating soil‐borne disease causing up to 80% yield losses in groundnut globally. To dissect the genetic basis of resistance, we evaluated a diverse minicore germplasm panel over 3 years in stem rot sick‐field conditions.
H. V. Veerendrakumar, Hari Kishan Sudini, Bangaru Kiranmayee, Talwar Devika, Sunil S. Gangurde, R. P. Vasanthi, A. R. Nirmal Kumar, Sandip K. Bera, Baozhu Guo, Boshou Liao, Rajeev K. Varshney, Manish K. Pandey   +11 more
wiley   +1 more source

An <i>in-cell</i> helicase reporter system for quantifying DDX3X and DDX3Y activities. [PDF]

Bioeng Transl Med
Poh ZS, Tan JCW, Wong BHS, Amuthavalli K, Kristanti H, Tan SH, Grigoropoulos NF, Verma NK.   +7 more
europepmc   +1 more source

A Novel UPF1 Variant Associated With a Rare UPF1 ‐Related Neurodevelopmental Disorder

Clinical Genetics, Volume 108, Issue 3, Page 313-317, September 2025.
Nonsense‐mediated mRNA decay (NMD) plays a crucial role in degrading aberrant transcripts with premature termination codons, and aberrant NMD has been linked to neurodevelopmental disorders (NDD). A key player of NMD is UPF1, which is a helicase. Including the current patient, only four individuals with NDD and UPF1 variants have been reported in the ...
Zeynep Tümer, Jonas Dalsberg, Gitte Rønde, Jesper Kiehn Sørensen, Elsebet Østergaard   +4 more
wiley   +1 more source

Severe Thrombocytopenia Is Associated with a Genetic Variant in the Helicase Domain of <i>SLFN14</i> Gene: A Case Report. [PDF]

EJHaem
Yang K, Fu P, Xu J, Jiang H, Yu J, Luo C, Gu J.   +6 more
europepmc   +1 more source

PARP Inhibitors in Genitourinary Cancer: A New Paradigm Beyond Prostate Cancer

International Journal of Urology, Volume 32, Issue 9, Page 1091-1101, September 2025.
ABSTRACT Alterations in the homologous recombination repair genes, such as BRCA1 and BRCA2, are prevalent in various cancers, presenting a unique opportunity to develop synthetic lethal strategies that target homologous recombination deficiency (HRD).
Yohei Okuda, Taigo Kato, Yu Ishizuya, Takuji Hayashi, Yoshiyuki Yamamoto, Koji Hatano, Atsunari Kawashima, Junko Murai, Norio Nonomura   +8 more
wiley   +1 more source

Gaining insights into epigenetic memories through artificial intelligence and omics science in plants

Journal of Integrative Plant Biology, Volume 67, Issue 9, Page 2320-2349, September 2025.
This review explores how artificial intelligence and machine learning predict plant behavior in response to environmental stress by modeling molecular regulatory networks of plant stress responses. Their combined application with omics methods opens new avenues in understanding the functioning of plant memory and future plant memory‐based plant ...
Judit Dobránszki, Valya Vassileva, Dolores R. Agius, Panagiotis Nikolaou Moschou, Philippe Gallusci, Margot M.J. Berger, Dóra Farkas, Marcos Fernando Basso, Federico Martinelli   +8 more
wiley   +1 more source

DDX3X and virus interactions: functional diversity and antiviral strategies. [PDF]

Front Microbiol
Ma S, Mao Q, Weng S, Teng M, Luo J, Zhang K.   +5 more
europepmc   +1 more source

Unravelling the dynamics of seed‐stored mRNAs during seed priming

New Phytologist, Volume 247, Issue 5, Page 2196-2209, September 2025.
Summary Seed priming is a pre‐sowing treatment that enables more efficient and uniform seed germination; however, it negatively affects seed longevity. In this work, the mRNA dynamics underlying a hydropriming treatment have been investigated. Polysome profiling was performed on seeds during different stages of hydropriming.
Patricija Gran, Tessa W. Visscher, Bing Bai, Harm Nijveen, Amir Mahboubi, Lars L. Bakermans, Leo A. J. Willems, Leónie Bentsink   +7 more
wiley   +1 more source