Results 91 to 100 of about 99,781 (250)

Peptic ulcer disease: Insights and risk factors

JPGN Reports, EarlyView.
Abstract Objectives Peptic ulcer disease (PUD), affects adults and children, with Helicobacter pylori (H. pylori) infection being the most frequent cause. Diagnosis requires an upper gastrointestinal endoscopy (UGE) and invasive tests. However, besides H. pylori, risk factors for PUD in children remain unclear.
Haidar Houmani, Islam Saidi, Meline M'rini, Julie Nguyen, Assaad Salame, Patrick Bontems, Kallirroi Kotilea   +6 more
wiley   +1 more source

Single-cell RNA profiling of colorectal granular-type laterally spreading tumor uncovers progression trajectory toward carcinoma and transcriptional signatures favoring lateral morphogenesis

Frontiers in Oncology
BackgroundColorectal laterally spreading tumors (LSTs) are defined as non-protruding neoplasms exceeding 10 mm in diameter that grow primarily along the intestinal wall.
Yueqing Gong, Yueqing Gong, Yuxin Zhang, Yuxin Zhang, Xun Liu, Xun Liu, Rongli Cui, Rongli Cui, Jingjing Lu, Jingjing Lu, Jun Li, Jun Li, Fang Gu, Fang Gu, Jing Zhang, Jing Zhang, Shigang Ding, Shigang Ding, Weiwei Fu, Weiwei Fu   +19 more
doaj   +1 more source

Turmeric and curcumin: From traditional medicine to modern therapeutic applications

JSFA reports, EarlyView.
Abstract Turmeric (Curcuma longa), a medicinal plant, has maintained its cultural and therapeutic significance over centuries in Ayurveda, Unani, and Traditional Chinese Medicine. However, novel formulations and delivery methods are being developed to address these challenges.
Azma Nadeem, Khurram Afzal, Asad Abbas, Talha Bin Iqbal, Abdul Malik, Javaria Saeed, Mutjardah Zarrish, Bipindra Pandey   +7 more
wiley   +1 more source

Simultaneous Detection of Caga and Cage of Helicobacter pylori Strains Recovered from Iranian Patients with Different Gastroduodenal Diseases

Iranian Journal of Public Health, 2009
Background: To asses the status of two representative genes of cag PAI i.e cagA and cagE of Helicobacter pylori strains infecting Iranian patients suffered from various clinical outcomes using one-step PCR. Methods: A total of 120 H.
M Douraghi , M Mohammadi , MH Shirazi, A Oghalaie , S Saberi Kashani , MA Mohagheghi, M Eshagh Hosseini , H Zeraati , M Esmaili , M Bababeik , N Mohajerani   +10 more
doaj  

Outcomes in the Management of Pediatric Retrograde Cricopharyngeal Dysfunction

The Laryngoscope, EarlyView.
ABSTRACT Objective To review the presentation and treatment outcomes of pediatric patients with retrograde cricopharyngeal dysfunction (RCPD). Methods A retrospective chart review was performed on pediatric patients diagnosed with retrograde cricopharyngeal dysfunction (RCPD) and treated with cricopharyngeal botulinum toxin injection (CPBTI).
Aidan P. Wright, Vivian Jin, Nathaniel B. Hunter, Andrew G. Tritter   +3 more
wiley   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Helicobacter pylori infection status and evolution of gastric cancer

Chinese Medical Journal
. Gastric cancer (GC) is a globally prevalent malignancy with a particularly heavy burden in China. Helicobacter pylori (H. pylori) is a Group I carcinogen for GC, with a higher seroprevalence rate indicating a higher GC incidence.
Wenlin Zhang, Yuxin Zhang, Jing Ning, Weiwei Fu, Shigang Ding, Yuanyuan Ji   +5 more
doaj   +1 more source

Analysis of the Matrix Metalloproteinases Family Profile in Gastric Cancer Suggests Key Matrix Metalloproteinases for Tumor Development and Their Clinical Impact

Molecular Carcinogenesis, EarlyView.
ABSTRACT Gastric cancer (GC) is the fifth most common type worldwide, representing a public health problem. Among the genes related to this tumorigenesis, the family of matrix metalloproteinases (MMPs), essential regulators of the extracellular matrix (ECM), stand out for their involvement in the development and progression of GC.
Aline Costa Bastos, André Salim Khayat, Emanuele Raimunda Louzada Moraes, Ágatha Tereza Miranda Tavares, Ronald Matheus da Silva Mourão, Fabiano Cordeiro Moreira, Samir Mansour Moraes Casseb, Samia Demachki, Geraldo Ishak, Williams Fernandes Barra, Rommel Mario Rodríguez Burbano, Paulo Pimentel de Assumpção   +11 more
wiley   +1 more source

A dietary combination of red yeast rice, phytosterol ester and lycopene ameliorates hypercholesterolemia by regulating gut microbiota and activating hepatic FXR-LDLR/ABCG pathway in mice

Frontiers in Microbiology
BackgroundExcessive nutrition intake is a well-established contributor to obesity and hypercholesterolemia, both of which pose substantial risks to cardiovascular health.
Jingxian Xu, Jingxian Xu, Xin Huang, Xin Huang, Fei Pei, Yuzhu Chen, Yuzhu Chen, Cunzheng Zhang, Cunzheng Zhang, Lingling Zhao, Hua Zhang, Jindong Zhang, Jindong Zhang, Liping Duan, Liping Duan   +14 more
doaj   +1 more source

The Emerging Role of Microbial Extracellular Vesicles in Neuroinflammation and Neurodegeneration

Medicine Bulletin, EarlyView.
ABSTRACT Neurodegenerative and neuropsychiatric disorders are increasingly viewed as systemic conditions shaped by interactions among peripheral immunity, microbiota, and the central nervous system. However, the mechanisms linking microbial activity to neuroinflammation and neurodegeneration remain poorly defined.
Julio Jesús Estrada‐Valbuena, Chao Li, Claudia M. Parra‐Giraldo, Raquel Martínez‐López   +3 more
wiley   +1 more source