Results 41 to 50 of about 164,924 (263)

Association of Helicobacter pylori vacA polymorphisms with the risk of gastric precancerous lesions in a Moroccan population

Journal of Infection in Developing Countries, 2021
Introduction: Helicobacter pylori infection is the major risk factor of atrophic gastritis and intestinal metaplasia. The vacA gene is one of the most virulence factors of H.
Mohamed Reda Jouimyi, Ghizlane Bounder, Imane Essaidi, Hasna Boura, Wafaa Badre, Hakima Benomar, Khalid Zerouali, Halima Lebrazi, Anass Kettani, Fatima Maachi   +9 more
doaj   +1 more source

Recent acquisition of Helicobacter pylori by Baka Pygmies [PDF]

, 2013
Both anatomically modern humans and the gastric pathogen Helicobacter pylori originated in Africa, and both species have been associated for at least 100,000 years. Seven geographically distinct H.
Linz, B., Nell, Sandra, Nkwescheu, Armand, Nell, S., Maady, A., Daniel Falush (46436), Yoshan Moodley (28753), Sebastian Suerbaum (61077), Eibach, D., Sandra Nell, Elamin, W., Falush, D., Siri, J., Nkwescheu, A., Bodo Linz, Sandra Nell (460595), Eibach, Daniel, Achtman, Mark, Jose Siri, Wael F. Elamin (460600), Ayas Maady, Falush, Daniel, Bodo Linz (165513), Wael F Elamin, Elamin, W.F., Achtman, M., Daniel Falush, Moodley, Yoshan, Linz, Bodo, Mark Achtman, Siri, Jose, Suerbaum, S., Maady, Ayas, Elamin, Wael F., Daniel Eibach, Montano, V., Ayas Maady (460597), Valeria Montano, Sebastian Suerbaum, Mark Achtman (126786), Siri, J.G., Suerbaum, Sebastian, Moodley, Y., Daniel Eibach (301821), Jose Siri (460599), Valeria Montano (460596), Yoshan Moodley, Armand Nkwescheu (460598), Montano, Valeria, Armand Nkwescheu   +49 more
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Faecal shedding of campylobacteria among domestic and wild animals from an urban coastal area

Austral Journal of Veterinary Sciences, 2019
Campylobacter jejuni and Campylobacter coli are the leading cause of food-related diarrhea worldwide. However, other campylobacteria such as other Campylobacter spp., Arcobacter spp. and Helicobacter spp.
Arturo Levican, Oriana Flores, Sergio Sanchez, María G. Bascuñan, Rafael Lopez, Karla Ojeda, Eduardo Hernandez, Pablo Salah   +7 more
doaj   +1 more source

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Long-term memory in epithelia: transient IFNγ exposure drives stable repression of TFF1 in gastric epithelial cells via epigenetic changes

Frontiers in Immunology
IntroductionInterferon-gamma (IFNγ) is a pro-inflammatory cytokine that is transiently produced and typically activates short-lived JAK–STAT1 signaling, yet it can also induce long-term transcriptional changes.
Antonia Voli, Daniela Eletto, Fatima Maria Mentucci, Chiara Centrella, Chiara Centrella, Martina Pannetta, Francesco Boccellato, Alfonso Finizio, Silvana Morello, Caterina Giraulo, Amalia Porta, Alessandra Tosco   +11 more
doaj   +1 more source

The SlyD metallochaperone targets iron-sulfur biogenesis pathways and the TCA cycle

mBio, 2023
Control of protein folding is a conserved function in all domains of life. The ubiquitous peptidyl-prolyl cis-trans isomerases (PPIases) catalyze the cis/trans-isomerization of peptidyl-prolyl bonds, often a rate-limiting step for protein folding ...
Milica Denic, Evelyne Turlin, Deborah B. Zamble, Jean-Michel Betton, Daniel Vinella, Hilde De Reuse   +5 more
doaj   +1 more source

An RGD helper sequence in CagL of Helicobacter pylori assists in interactions with integrins and injection of CagA [PDF]

, 2012
Conradi J, Tegtmeyer N, Wozna M, et al. An RGD helper sequence in CagL of Helicobacter pylori assists in interactions with integrins and injection of CagA. Frontiers in Cellular and Infection Microbiology.
Backert, Steffen, Tegtmeyer, Nicole, Timothy L Cover, Steffen Backert, Gagell, Corinna, Marta eWoźna, Marco eWissbrock, Cover, Timothy L., Sewald, Norbert ; https://orcid.org/, Michalek, Carmela, Frank, Ronald, Ronald eFrank, Norbert eSewald, Jens eConradi, Nicole Tegtmeyer, Carmela Michalek, Corinna eGagell, Jens Conradi, Steffen eBackert, Norbert Sewald, Carmela eMichalek, Marco Wissbrock, Wißbrock, Marco, Timothy L. Cover, Wozna, Marta, Marta Woźna, Corinna Gagell, Ronald Frank, Conradi, Jens, Nicole eTegtmeyer   +29 more
core   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source