Results 41 to 50 of about 103,253 (257)

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Association Between Vitamin D Receptor Polymorphism and the Response to Helicobacter Pylori Treatment

Infection and Drug Resistance, 2023
Yousry Esam-Eldin Abo-Amer,1 Amal Ahmed Mohamed,2 Mohamed Mahmoud Elhoseeny,3 Samar M Rezk,4 Sherief Abdel-Salam,5 Abdulmohsen H Alrohaimi,6 Asmaa Sayed Abdelgeliel,7 Seham Saeed Alzahrani,8 Ibrahim Jafri,8 Leena S Alqahtani,9 Eman Fayad,8 Mohamed Fakhry,
Abo-Amer YEE, Mohamed AA, Elhoseeny MM, Rezk SM, Abdel-Salam S, Alrohaimi AH, Abdelgeliel AS, Alzahrani SS, Jafri I, Alqahtani LS, Fayad E, Fakhry M, Soliman MY   +12 more
doaj  

Enterohepatic Helicobacter other than Helicobacter pylori [PDF]

Revista Española de Enfermedades Digestivas, 2013
The Helicobacter genus includes Gram negative bacteria which were originally considered to belong to the Campylobacter genus. They have been classified in a separate genus since 1989 because they have different biochemical characteristics, with more than 24 species having been identified and more still being studied.H. pylori is the best known.
Mateos Muñoz, Beatriz, Pérez de la Serna, Julio, Ruiz de León, Antonio, Serrano Falcón, Blanca, Casabona Francés, Sergio, Velasco Cerrudo, Aurelio, Rey Díaz-Rubio, Enrique   +6 more
openaire   +4 more sources

Review: Non-Helicobacter pylori Helicobacters

Microbiota in Health and Disease, 2022
This article reviews the most important and relevant literature published between April 2021 and March 2022 on non-Helicobacter pylori Helicobacter (NHPH) infections in humans and animals. Of note, Helicobacter delphinicola was newly described in this period. The first part of this review focuses on the literature describing gastric NHPH. Many clinical
Nakamura, M., Murayama, S. Y., Rimbara, E.   +2 more
openaire   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Prevalence of helicobacter pylori in patients undergoing upper GI endoscopy in hospital No 1 Kerman university of medical sciences [PDF]

Journal of Kerman University of Medical Sciences, 1994
Prevalence of helicobacter pylori was evaluated by urease test in 513 patients undergoing GI endoscopy, in hospital No1 Kerman university of medical sciences and health services from June 1992 through April 1993. H. Pylori was detected in 56.9℅ of tested
H Jojaji
doaj  

Misidentifying Helicobacters: the Helicobacter cinaedi Example [PDF]

Journal of Clinical Microbiology, 2000
ABSTRACT Whole-cell protein electrophoresis and biochemical examination by means of a panel of 64 tests were used to identify 14 putative helicobacters to the species level. The results were confirmed by means of DNA-DNA hybridization experiments and were used to discuss misidentification of helicobacters based on 16S rRNA gene ...
P, Vandamme, C S, Harrington, K, Jalava, S L, On   +3 more
openaire   +2 more sources

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Evaluación de métodos de extracción de ADN bacteriano en muestras fecales de pacientes diagnosticados con infección por Helicobacter pylori

Biociencias, 2018
La identificación de microorganismos a través de técnicas moleculares ha tomado gran popularidad en los últimos años gracias a su precisión. La Reacción en Cadena de la Polimerasa (PCR) es una téc-nica de diagnóstico molecular sumamente valorada ...
Aracely García Cuan
doaj   +1 more source