Results 51 to 60 of about 276,829 (341)

Single-cell RNA profiling of colorectal granular-type laterally spreading tumor uncovers progression trajectory toward carcinoma and transcriptional signatures favoring lateral morphogenesis

Frontiers in Oncology
BackgroundColorectal laterally spreading tumors (LSTs) are defined as non-protruding neoplasms exceeding 10 mm in diameter that grow primarily along the intestinal wall.
Yueqing Gong, Yueqing Gong, Yuxin Zhang, Yuxin Zhang, Xun Liu, Xun Liu, Rongli Cui, Rongli Cui, Jingjing Lu, Jingjing Lu, Jun Li, Jun Li, Fang Gu, Fang Gu, Jing Zhang, Jing Zhang, Shigang Ding, Shigang Ding, Weiwei Fu, Weiwei Fu   +19 more
doaj   +1 more source

Helicobacter pylori: types of diseases, diagnosis, treatment and causes of therapeutic failure [PDF]

, 2016
Acute upper gastrointestinal lesions have a multifactorial etiology but, regardless of the cause, they are related to mucosal barrier destruction. Since Helicobacter pylori induces a superficial chronic gastritis with the infiltration of neutrophils in ...
Ciorbagiu, Mihai Calin, Mirea, Cecil Sorin, Moraru, Emil, Obleaga, Cosmin Vasile, Valcea, Ionica Daniel, Vere, Cristin Constantin   +5 more
core   +3 more sources

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Revealing the pathogenesis of gastric intestinal metaplasia based on the mucosoid air-liquid interface

Journal of Translational Medicine
Background Gastric intestinal metaplasia (GIM) is an essential precancerous lesion. Although the reversal of GIM is challenging, it potentially brings a state-to-art strategy for gastric cancer therapeutics (GC).
Simeng Liu, Huijuan Wen, Fazhan Li, Xia Xue, Xiangdong Sun, Fuhao Li, Ruoyu Hu, Huayuan Xi, Francesco Boccellato, Thomas F Meyer, Yang Mi, Pengyuan Zheng   +11 more
doaj   +1 more source

A dietary combination of red yeast rice, phytosterol ester and lycopene ameliorates hypercholesterolemia by regulating gut microbiota and activating hepatic FXR-LDLR/ABCG pathway in mice

Frontiers in Microbiology
BackgroundExcessive nutrition intake is a well-established contributor to obesity and hypercholesterolemia, both of which pose substantial risks to cardiovascular health.
Jingxian Xu, Jingxian Xu, Xin Huang, Xin Huang, Fei Pei, Yuzhu Chen, Yuzhu Chen, Cunzheng Zhang, Cunzheng Zhang, Lingling Zhao, Hua Zhang, Jindong Zhang, Jindong Zhang, Liping Duan, Liping Duan   +14 more
doaj   +1 more source

Functional plasticity in the type IV secretion system of Helicobacter pylori. [PDF]

, 2012
Helicobacter pylori causes clinical disease primarily in those individuals infected with a strain that carries the cytotoxin associated gene pathogenicity island (cagPAI).
Barrozo, Roberto M, Cariaga, Taryn A, Cooke, Cara L, Cover, Timothy L, Gaddy, Jennifer A, Hansen, Lori M, Johnson, Elizabeth M, Lam, Anna M, Peek, Richard M, Solnick, Jay V, Suarez, Giovanni   +10 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Insights from the redefinition of Helicobacter pylori lipopolysaccharide O-antigen and core-oligosaccharide domains

Microbial Cell, 2017
H. pylori is a Gram-negative extracellular bacterium, first discovered by the Australian physicians Barry Marshall and Robin Warren in 1982, that colonises the human stomach mucosa.
Hong Li, Tiandi Yang, Tingting Liao, Aleksandra W. Debowski, Hans-Olof Nilsson, Stuart M. Haslam, Anne Dell, Keith A. Stubbs, Barry J. Marshall, Mohammed Benghezal   +9 more
doaj   +1 more source

A comparative study of clinicopathological features between chronic cholecystitis patients with and without Helicobacter pylori infection in gallbladder mucosa. [PDF]

PLoS ONE, 2013
BACKGROUND: Helicobacter pylori has been isolated from 10%-20% of human chronic cholecystitis specimens but the characteristics of "Helicobacter pylori positive cholecystitis" remains unclear.
Di Zhou, Wen-bin Guan, Jian-dong Wang, Yong Zhang, Wei Gong, Zhi-wei Quan   +5 more
doaj   +1 more source

Extragastroduodenal conditions associated with Helicobacter pylori infection [PDF]

, 1999
Helicobacter pylori is a Gram-negative bacterium that is considered a causative agent of peptic ulcer disease, gastric lymphoma, and gastric carcinoma.
Lam, SK, Tsang, KWT
core