Results 51 to 60 of about 280,543 (339)

Insights from the redefinition of Helicobacter pylori lipopolysaccharide O-antigen and core-oligosaccharide domains

Microbial Cell, 2017
H. pylori is a Gram-negative extracellular bacterium, first discovered by the Australian physicians Barry Marshall and Robin Warren in 1982, that colonises the human stomach mucosa.
Hong Li, Tiandi Yang, Tingting Liao, Aleksandra W. Debowski, Hans-Olof Nilsson, Stuart M. Haslam, Anne Dell, Keith A. Stubbs, Barry J. Marshall, Mohammed Benghezal   +9 more
doaj   +1 more source

The effect of microRNA-375 overexpression, an inhibitor of Helicobacter pylori-induced carcinogenesis, on lncRNA SOX2OT [PDF]

, 2016
Background: Helicobacter pylori is a major human pathogenic bacterium in gastric mucosa. Although the association between gastric cancer and H. pylori has been well-established, the molecular mechanisms underlying H.
Aleyasin, S.A., Mowla, S.J., Shafiee, M., Vasei, M., Yazdanparast, S.A.   +4 more
core   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth. [PDF]

, 2015
Lymphoid tissue inducer (LTi) cells are activated by accessory cell IL-23, and promote lymphoid tissue genesis and antibacterial peptide production by the mucosal epithelium.
Banerjee, A, Basappa, N, Blanchard, TG, Czinn, SJ, Ding, H, Drakes, ML, Fricke, WF, Kobayashi, KS, Piazuelo, MB, Shiu, J   +9 more
core   +2 more sources

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

Revealing the role of metformin in gastric intestinal metaplasia treatment

Frontiers in Pharmacology
ObjectiveGastric intestinal metaplasia (IM) is a precancerous stage associated with gastric cancer. Despite the observed beneficial effects of metformin on IM, its molecular mechanism remains not fully elucidated.
Ruoyu Hu, Ruoyu Hu, Xia Xue, Xiangdong Sun, Yang Mi, Huijuan Wen, Huijuan Wen, Huayuan Xi, Huayuan Xi, Fuhao Li, Fuhao Li, Pengyuan Zheng, Pengyuan Zheng, Simeng Liu, Simeng Liu   +14 more
doaj   +1 more source

Causal relationship between Helicobacter pylori antibodies and gastroesophageal reflux disease (GERD): A mendelian study.

PLoS ONE, 2023
BackgroundObservational studies have indicated that both Helicobacter pylori infection and the presence of Helicobacter pylori antibodies may increase the risk of gastroesophageal reflux disease (GERD). However, the exact association between Helicobacter
Jiaqin Chen, Junning Zhang, Xiaolu Ma, Yuehan Ren, Yi Tang, Zhongmian Zhang, Wangyu Ye, Xiyan Zhang, Zili Lin, Lan Wang, Zhihong Li   +10 more
doaj   +1 more source

Helicobacter pylori catalase [PDF]

Microbiology, 1991
Summary:Helicobacter pyloriis the major aetiological agent of gastroduodenitis in humans. Due to the potential importance of catalase in the growth and survival ofHelicobacter pylorion the surface of inflamed mucosae, we have characterized catalase fromH. pylorias a prelude to further studies on the function of the enzymein vivo.
S L, Hazell, D J, Evans, D Y, Graham
openaire   +2 more sources