Results 151 to 160 of about 68,269 (251)
This work systematically explored the anti‐chronic gastritis mechanism of the FAI‐BCT herb pair. UPLC‐Q‐TOF‐MS/MS was applied to identify absorbed prototypes and metabolites of FAI‐BCT in rat plasma. Combining database mining, network pharmacology, molecular docking, and molecular dynamics simulation, we screened the key bioactive components and core ...
Yinghua Ma +4 more
wiley +1 more source
Effects of supplementing with Saccharomyces boulardii on vonoprazan-amoxicillin dual therapy for naive Helicobacter pylori infection: a randomized controlled trial. [PDF]
Ji Z, Qu D, Feng Y, Qin X, Wang X.
europepmc +1 more source
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam +3 more
wiley +1 more source
Chlorogenic acid (CGA) inhibits Helicobacter pylori urease (HPU) through a mixed‐type mechanism. The CGA–HPU interaction is thermodynamically spontaneous and enthalpy‐driven (ΔG < 0, ΔH < 0), proceeding via a static quenching mode. Molecular dynamics simulations and structural studies reveal that CGA binds near the HPU active site and mobile flap ...
Luzhe Wu +6 more
wiley +1 more source
Helicobacter pylori infection and liver function alterations in individuals undergoing gastric cancer screening: a cohort study. [PDF]
Feizi I +4 more
europepmc +1 more source
ABSTRACT Background and Aims Although upper gastrointestinal (GI) endoscopy is a crucial diagnostic tool for evaluating lesions of the upper GI tract, its findings are not always definitive, necessitating histopathological confirmation. This retrospective study aimed to assess the spectrum of histopathological lesions and their correlation with ...
Prosper Adjei, Samuel Kyeremeh Adjei
wiley +1 more source
Construction of a Prognostic Risk Model for Helicobacter pylori Infection in Gastric Cancer Patients and Immunological Analysis. [PDF]
Tian Z, Su M, Yang B, Zhang Z, Zhang L.
europepmc +1 more source
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang +5 more
wiley +1 more source
WeChat-based manual enhanced guidance in patients with Helicobacter pylori infection. [PDF]
Shi X +6 more
europepmc +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source

