Results 281 to 290 of about 139,635 (334)

Co‐Infection by Porphyromonas gingivalis and Fusobacterium nucleatum Increases PD‐L1 Expression in Esophageal Cancer Tissues

open access: yesMicrobiologyOpen, Volume 14, Issue 4, August 2025.
Porphyromonas gingivalis and Fusobacterium nucleatum (Fn) co‐infection increases PD‐L1 expression in esophageal cancer, aiding immune escape; eliminating them may reduce progression and recurrence. ABSTRACT Currently, the impact of the microbiome on the progression and recurrence of esophageal cancer remains unclear.
Xiayi Lin   +6 more
wiley   +1 more source

Assessment of adverse pregnancy outcomes associated with Helicobacter pylori infection. [PDF]

open access: yesSci Rep
Wang SJ   +6 more
europepmc   +1 more source

Toll‐Like Receptors in the Immunotherapy Era: Dual‐Edged Swords of Tumor Immunity and Clinical Translation

open access: yesMedComm, Volume 6, Issue 8, August 2025.
This review discussed the signaling pathways of Toll‐like receptors in tumors and their antitumor or protumor regulatory effects in diverse tumors. We also paid attention to the application of Toll‐like receptors in clinical treatment and summarized the clinical trial situation in recent years.
Nueraili Maihemuti   +7 more
wiley   +1 more source

Efficacy of High‐Dose Intravenous Anakinra in Pediatric TAFRO Syndrome: Report of Two Cases and Literature Review

open access: yesPediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly) syndrome is a rare, life‐threatening inflammatory condition linked to infections, neoplasms, and idiopathic multicentric Castleman disease. Interleukin (IL)‐6 inhibitors are the primary treatment, but refractory cases require alternatives. This
Serena Palmeri   +10 more
wiley   +1 more source

Potential Kidney Risks Associated With Clinical Doses of Omeprazole: In Vivo and In Vitro Studies

open access: yesClinical and Experimental Pharmacology and Physiology, Volume 52, Issue 8, August 2025.
Omeprazole decreases cell proliferation and viability by disrupting gene expression; thus, the long‐term use of omeprazole may increase inflammation and environmental susceptibility. These findings provide valuable insights for the clinical use of omeprazole, highlighting the need for careful consideration of its effects in the kidney.
Zibo Xiong   +7 more
wiley   +1 more source

Clonal Hematopoiesis and Solid Cancers

open access: yesCancer Science, Volume 116, Issue 8, Page 2055-2063, August 2025.
This review explores the relationship between clonal hematopoiesis and solid cancers. Clonal hematopoiesis mutations influence the tumor microenvironment by altering immune regulation, inflammation, and angiogenesis. Understanding these mutations has important clinical implications, including their role in prognosis, treatment response, and potential ...
Yen T. M. Nguyen   +3 more
wiley   +1 more source

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