Results 91 to 100 of about 58,691 (223)
Allergy, EarlyView.ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan +5 more
wiley +1 more source
Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR [PDF]
, 2012 BACKGROUND: Albendazole and mebendazole are increasingly deployed for preventive chemotherapy targeting soil-transmitted helminth (STH) infections. We assessed the efficacy of single oral doses of albendazole (400 mg) and mebendazole (500 mg) for the ...
Sayasone, S. +40 more
core +2 more sources
Dietary Habits and Atopic Dermatitis Significantly Influence the Fecal Microbiome
Allergy, EarlyView.Atopic dermatitis, dietary habits, sex, and BMI significantly influenced the fecal microbiome composition. On the species level, Faecalibacterium taiwanense was more abundant in atopic dermatitis, and Vescimonas sp000435555 was more abundant in the control population. On the genus level, CAG‐302 (NCBI: Clostridium) was more abundant in controls.
Danielle Fehr +14 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe +24 more
wiley +1 more source
Impact of Anthelminthic Treatment in Pregnancy and Childhood on Immunisations, Infections and Eczema in Childhood : A Randomised Controlled Trial [PDF]
, 2012 Helminth infections may modulate immune responses to unrelated pathogens and allergens; these effects may commence prenatally. We addressed the hypothesis that anthelminthic treatment in pregnancy and early childhood would improve responses to ...
Mpairwe, Harriet +20 more
core +3 more sources
Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases
Allergy, EarlyView.ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz +22 more
wiley +1 more source
Acta Zoologica, EarlyView.ABSTRACT This study presents a formal description and taxonomic appraisal of Cacatuocotyle adrianoi sp. n., a Neotropical parasite belonging to the family Dactylogyridae, integrating AI‐assisted morphometric analyses, molecular data, and phylogenetic reconstruction. Phylogenetic analyses recovered Cacatuocotyle adrianoi sp. n.
J. C. C. Aguiar +4 more
wiley +1 more source
Mucosal immune responses following intestinal nematode infection. [PDF]
, 2014 In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Harris, N. L. +9 more
core +1 more source
Health Research Funders and Justice: Obligations to Coordinate and Counterbalance
Bioethics, EarlyView.ABSTRACT Government health research funders are frequently criticized on the grounds that their distribution of resources fails to reflect a population's disease burden. These critiques do not take into account what other research funders are doing. In this paper, I argue that this is a mistake.
Joseph Millum
wiley +1 more source
Lower expression of TLR2 and SOCS-3 is associated with Schistosoma haematobium infection and with lower risk for allergic reactivity in children living in a rural area in Ghana. [PDF]
, 2008 BACKGROUND: Helminth infections are prevalent in rural areas of developing countries and have in some studies been negatively associated with allergic disorders and atopy. In this context little is known of the molecular mechanisms of modulation involved.
Larbi, Irene A. +42 more
core +1 more source