Results 91 to 100 of about 1,881,560 (314)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The ex-client’s experience of attitudinal and structural barriers to therapy, prior to and during the therapeutic relationship [PDF]

, 2011
People’s reluctance to seek/secure counselling/psychotherapy is an area requiring further attention. This study sought to add to existing research by undertaking phenomenological interviews exploring ex-clients experiences of seeking/securing help.
Hunt, Andrew C.
core  

Adolescent Relationship Violence: Help-Seeking and Help-Giving Behaviors among Peers

, 2014
Young people tend to disclose relationship violence experiences to their peers, if they disclose at all, yet little is known about the nature and frequency of adolescent help-seeking and help-giving behaviors.
Messinger, Adam M., Palmetto, Niki, Fry, Deborah A., Lessel, Harriet, Davidson, Leslie L., Rickert, Vaughn I., O’Connor, Meghan K.   +6 more
core   +1 more source

The help relationship in nursing

, 2014
© 2014 Fundación Index. This document is the Published version of a Published Work that appeared in final form in Index de Enfermería.La Enfermería es una profesión basada en la relación entre la enfermera y aquella persona que requiere de sus cuidados ...
Morales Moreno, Isabel, Bermejo Higuera, José Carlos, Muñoz Devesa, Aarón, Galán González-Serna, José María   +3 more
core   +1 more source

Culture moderates the relationship between socially prescribed perfectionism and stigma towards help-seeking among college athletes

Discover Mental Health
In this study, the relationship between socially prescribed perfectionism, perfectionistic self-presentation, cultural orientation, and stigma towards help-seeking among college athletes was examined.
Kellie Courtney, Brandon Dial, Danielle Key, Ella Gibson, Wen Ying Chen, Philip T. Yanos   +5 more
doaj   +1 more source

The relationship between mental health literacy and professional psychological help-seeking behavior among Chinese college students: mediating roles of perceived social support and psychological help-seeking stigma

Frontiers in Psychology
IntroductionMental health literacy is viewed as a significant factor that may facilitate an individual’s pursuit of professional psychological assistance.
Xiao Yang, Jun Hu, Bingren Zhang, Hua Ding, Danying Hu, Hangdong Li   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Assessing the Landscape of Relationship Help and a Pilot Adaptation of Relationship Checkups for Christian Churches

, 2023
The health and stability of adult romantic relationships and the health of a society are deeply intertwined. This two-part dissertation aims to highlight the potential to bridge the gap between effective interventions and couples who need them most.
York, Adam W
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Exploring the Relationship Between Public Stigma, Self-Stigma, and Counselling Help-Seeking Intentions Among Adolescents in Madrasah

COUNS-EDU: The International Journal of Counseling and Education
To improve the mental well-being of adolescents is that there is no intention to seek psychological help. This study aims to explore the relationship between public stigma, self-stigma, and the intention to seek psychological help among adolescents who ...
Ika Ariyati
doaj   +1 more source