Results 41 to 50 of about 6,735,850 (224)

Fluorescent protein-expressing Modified Vaccinia Ankara encoding T7 RNA polymerase

Journal of Virology
Efficient recovery of negative-stranded RNA viruses from plasmid cDNA requires robust bacteriophage T7 RNA polymerase expression, commonly supplied by Modified Vaccinia Ankara expressing T7 polymerase (MVA T7).
Nathaniel Jackson, Mahmoud Bayoumi, Himadri Nath, Luis Martinez-Sobrido   +3 more
doaj   +1 more source

Impact of Chronic Viral Infection on T-Cell Dependent Humoral Immune Response

Frontiers in Immunology, 2017
During the last decades, considerable efforts have been done to decipher mechanisms supported by microorganisms or viruses involved in the development, differentiation, and function of immune cells. Pathogens and their associated secretome as well as the
Stéphane Rodriguez, Stéphane Rodriguez, Mikaël Roussel, Mikaël Roussel, Karin Tarte, Karin Tarte, Patricia Amé-Thomas, Patricia Amé-Thomas   +7 more
doaj   +1 more source

Intranasal Delivery of Inactivated Influenza Virus and Poly(I:C) Adsorbed Corn-Based Nanoparticle Vaccine Elicited Robust Antigen-Specific Cell-Mediated Immune Responses in Maternal Antibody Positive Nursery Pigs

Frontiers in Immunology, 2020
We designed the killed swine influenza A virus (SwIAV) H1N2 antigen (KAg) with polyriboinosinic:polyribocytidylic acid [(Poly(I:C)] adsorbed corn-derived Nano-11 particle based nanovaccine called Nano-11-KAg+Poly(I:C), and evaluated its immune correlates
Veerupaxagouda Patil, Veerupaxagouda Patil, Sankar Renu, Sankar Renu, Ninoshkaly Feliciano-Ruiz, Ninoshkaly Feliciano-Ruiz, Yi Han, Yi Han, Anikethana Ramesh, Anikethana Ramesh, Jennifer Schrock, Jennifer Schrock, Santosh Dhakal, Santosh Dhakal, Harm HogenEsch, Gourapura J. Renukaradhya, Gourapura J. Renukaradhya   +16 more
doaj   +1 more source

CRISPR/CAS9: A TOOL TO CIRCUMSCRIBE COTTON LEAF CURL DISEASE

Frontiers in Plant Science, 2016
The begomoviruses (family Geminiviridae) associated with cotton leaf curl disease (CLCuD) pose a major threat to cotton productivity in South-East Asia including Pakistan and India.
Zafar eIqbal, Muhammad Naeem Sattar, Muhammad eShafiq   +2 more
doaj   +1 more source

Detection of pks Island mRNAs Using Toehold Sensors in Escherichia coli

Life, 2021
Synthetic biologists have applied biomolecular engineering approaches toward the goal of novel biological devices and have shown progress in diverse areas of medicine and biotechnology.
Taeyang Heo, Hansol Kang, Seungdo Choi, Jongmin Kim   +3 more
doaj   +1 more source

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Influence of dendritic cells on viral pathogenicity. [PDF]

PLoS Pathogens, 2009
Although most viral infections cause minor, if any, symptoms, a certain number result in serious illness. Viral disease symptoms result both from direct viral replication within host cells and from indirect immunopathological consequences.
Giulia Freer, Donatella Matteucci
doaj   +1 more source

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna, Alexia Muresan, Estelle Lecluze, Karine Leduc, Nathalie Fournier, Maria Tamer, Jean‐François Delisle, Jeremi Charbonneau, Annie Viau, Jessica Darilus, Marie‐Joëlle Doré‐Bergeron, Valérie Arsenault, Evelyne Doyon‐Trottier, Stéphanie Forte, Nancy Robitaille, Yves Pastore, Thomas Pincez   +16 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source