Results 101 to 110 of about 3,465,634 (408)
Anxiolytic Treatment Impairs Helping Behavior in Rats
Despite decades of research with humans, the biological mechanisms that motivate an individual to help others remain poorly understood. In order to investigate the roots of pro-sociality in mammals, we established the helping behavior test, a paradigm in
I. Ben-Ami Bartal +6 more
semanticscholar +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Can group rewards promote helping in asymmetrically imbalanced task relationships?
This paper investigated whether group-level rewards can counteract the negative effects of asymmetric task dependence. Previous research has found that asymmetry (an imbalance in task-related resources, such as work inputs, knowledge, or skills) is ...
Christopher Poile, Frank Safayeni
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Nurturing faculty research and scholarship is a top priority for the law school.
Naismith, Veronica L.
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
I’ll be there for you? The bystander intervention model and cyber aggression
The Bystander Intervention Model (BIM) has been validated for face-to-face emergencies and dictates that observers’ decision to intervene hinges on five sequential steps, while barriers block progress between steps.
Vasileia Karasavva, Amori Mikami
doaj +1 more source
Dry Bones Live: Helping Congregations Discover New Life [PDF]
Reviewed Book: Craig, Robert H. Dry Bones Live: Helping Congregations Discover New Life.
Diegel, Matthew H.
core +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source

