About the difficult art of helping. Book reviev Refugees Among Us Aid in an Interdisciplinary Perspective edited by Ewa Kurantowicz [PDF]
The article is a discussion of a book dedicated to aid activities addressed to refugees from Ukraine after the start of hostilities. The reviewed book was based on projects which showed the socio-cultural dimension of helping.
Witold Jakubowski
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Level of physical Activity in Patients with Fatty Liver - A Cross Sectional study
Background: Liver with fatty appearance illness is a common disorder that is caused by addition of extra fats in the liver. Fats make up 5% to 10% of the weight of the liver, it becomes an issue and it is termed as steatosis.
Adnan Ahmed +5 more
doaj
I’ll be there for you? The bystander intervention model and cyber aggression
The Bystander Intervention Model (BIM) has been validated for face-to-face emergencies and dictates that observers’ decision to intervene hinges on five sequential steps, while barriers block progress between steps.
Vasileia Karasavva, Amori Mikami
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
RWU, RWU Law to Offer Scholarships to Displaced Students from Syria [PDF]
University joins Institute for International Education’s Syria Consortium in helping architecture and law students to resume studies in ...
Public Affairs, Roger Williams University
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Impact of cervicogenic headache on work productivity: A Cross-Sectional Survey
Background: One-sided, recurring headache that generally comes with neck pain and stiffness are associated with cervicogenic headache. These headaches have frequent episodes lately, and they alter people’s day to day routines and quality of work.
Misbah Binte Ilyas +3 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

