Results 121 to 130 of about 742,438 (343)

Rolul emoţiilor în cercetarea comportamentului prosocial. Merită să-i ajuţi pe alţii!

open access: yesSociologie Românească, 2008
The article compares rational choice, evolution and empathy paradigm in relation with prosocial behaviour explanation. It brings into discussion personal aspects that interfere with the emergency of helping behaviour, especially the social value ...
Loredana Ivan
doaj  

Experimental paradigm to test the effects of providing social support: study protocol of the PROSPECT trial (Study 2)

open access: yesBMC Psychology
Background A growing body of research suggests that the provision of social support can have benefits not only for the recipients but also for the provider.
Vivien Hajak   +5 more
doaj   +1 more source

The Effectiveness of Interventions to Improve Mental Health Literacy, Helping Behaviours and Stigmatizing Attitudes in Schoolteachers and Staff in Asian Countries: A Systematic Review and Meta-analysis

open access: yesJournal of the College of Community Physicians
Introduction: Mental health literacy (MHL) has been defined as the knowledge and beliefs about mental disorders which aid their recognition, management or prevention.
Buddhini Denuwara   +4 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

The implications of real-time behavioural tracking [PDF]

open access: yes, 2009
In contrast to offline gambling, behavioural tracking presents an opportunity for gaming operators and researchers to examine the actual and real-time behaviour engaged in by gamblers. To date, almost all diagnostic screening instruments contain criteria
Griffiths, MD
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Development of psychosocial case studies by students to improve their ability to understand and analyze human behavior [PDF]

open access: yes, 2017
This study presents an active learning methodology based on the development and analysis of case studies by college students and explores its effects on academic performance and on students' capacity of understanding and analysing human behaviour.
Castrechini Trotta, Ángela   +9 more
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Help motivation: Preconditions for altruistic behaviour

open access: yesPsichologija, 1991
Social and biological treatments of help motivation, the decision-making dynamics of helping processes of personality due to situation conditions and to other factors are discussed. The key notions of the article are victim motive conflict, challenge to self-esteem. Mechanisms of receiving help and personality characteristics of help receiving are also
openaire   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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