Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
The relationship of sexual and gender-based violence (SGBV) to sexual-risk behavior among refugee women in Botswana: The mediating role of depression [PDF]
THE RELATIONSHIP OF SEXUAL AND GENDER-BASED VIOLENCE (SGBV) TO SEXUAL RISK BEHAVIORS AMONG REFUGEE WOMEN IN BOTSWANA: THE MEDIATING ROLE OF DEPRESSIONJohannes John-Langba, Ph.D., M.P.H.University of Pittsburgh, 2004This study investigated the ...
John-Langba, Johannes
core
The Role of Hardiness in Moderating the Relationship between Global/Specific Attributions and Actions against Discrimination [PDF]
In this study, we proposed that individual differences in hardiness may moderate the relationship between global attributions and actions against discrimination.
Dion, Kenneth L., Foster, Mindi D
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Objectives To explore the multiple mediating roles of the learned helplessness’s core system in the relationship between health literacy/social support and self-management.Design Cross-sectional survey design.Setting Changsha, China.Participants 239 ...
Li Li +5 more
doaj +1 more source
Self-Defeating Personality and Learned Helplessness [PDF]
This study attempted to determine whether people who engage in a higher frequency of self-defeating behaviors show a greater degree of those characteristics which define learned helplessness.
Kabatay, Regina T.
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Effectiveness of Motivational Intervention Based on Mind Set on Academic Procrastination and Learned Helplessness [PDF]
The purpose of this study was to the effectiveness of motivational intervention based on mind set on academic procrastination and learned helplessness of students.The research method was quasi-experimental with pretest-posttest design and control group ...
maryam sanami +2 more
doaj +1 more source
Interrogation or Experimentation? Assessing Non-Consensual Human Experimentation During the War on Terror [PDF]
The prohibition against non-consensual human experimentation has long been considered sacrosanct. It traces its legal roots to the Nuremberg trials although the ethical foundations dig much deeper.
Aceves, William J.
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Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source

