Results 71 to 80 of about 103,008 (284)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Overview of diagnostic methods attributive style and learned helplessness [PDF]

, 2016
Публікація присвячена аналізу зарубіжних та вітчизняних методик діагностики атрибутивного стилю та навченої безпорадності. Описані діагностичні можливості методики контент–аналізу вербальних пояснень CAVE, методики діагностики атрибутивного стилю для ...
Клібайс, Тетяна Володимирівна
core  

Academic achievement : the role of praise in motivating students [PDF]

, 2005
The motivation of students is an important issue in higher education, particularly in the context of the increasing diversity of student populations.
AMES, R., BANDURA, A., BIGGS, J., DART, B., DWECK, C., DWECK, C., Effie Maclellan, ELLIOT, J., GRAHAM, S., HATTIE, J., HOWARD, S., KAPLAN, A., KNIGHT, P., KNIGHT, P., KRAPP, A., LEO, E., MASTEN, A., MILLER, R., PINTRICH, P., PINTRICH, P., PROSSER, M., ROBINS, R., RYAN, R., SCHULLER, T., SCHUNK, D., SELIGMAN, M.   +25 more
core   +2 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

C1q deletion exacerbates stress-induced learned helplessness behavior and induces neuroinflammation in mice

Translational Psychiatry, 2022
Increased levels of pro-inflammatory cytokines have been reported in postmortem brain samples and in the blood of depressed subjects. However, the inflammatory pathways that lead to depressive-like symptoms are not well understood.
Amit Kumar Madeshiya, Carl Whitehead, Ashutosh Tripathi, Anilkumar Pillai   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

The effect of students' effort–reward imbalance on learning engagement: the mediating role of learned helplessness and the moderating role of social support

Frontiers in Psychology
IntroductionTo explore the predictive effect of effort–reward imbalance on students' learning engagement and to elucidate the underlying mechanism, 796 students were selected for a survey.MethodsThe participants were required to complete four scales: the
Shengmin Liu, Yuanru Wang, Wanning He, Yu Chen, Qiangqiang Wang   +4 more
doaj   +1 more source

Learned Helplessness in Renal Dialysis Patients: Concept Analysis with an Evolutionary Approach

Patient Preference and Adherence, 2022
Chunyan Xie,1,2 Li Li,1– 3 Yamin Li1 1Clinical Nursing Teaching and Research Section, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China; 2XiangYa Nursing School, Central South University, Changsha,
Xie C, Li L, Li Y
doaj  

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu, Talia Robinson, Marina Rodriguez Alonso, Adela Francis Malave, Roos J. Jutten, Michael J. Properzi, Brian C. Healy, Jackson C. Thompson, Grace Del Carmen Montenegro, Emma Thibault, Dana Penney, Randall Davis, Reisa A. Sperling, Kathryn V. Papp, Keith A. Johnson, Julie C. Price, Dorene M. Rentz   +16 more
wiley   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source