Results 51 to 60 of about 16,169 (166)

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Serologically-Based Evaluation of Cross-Protection Antibody Responses among Different A(H1N1) Influenza Strains

Vaccines, 2020
After the influenza H1N1 pandemic of 2009, the seasonal A/Brisbane/59/2007 strain was replaced by the A/California/07/2009 strain for the influenza virus vaccine composition. After several seasons with no indications on the occurrence of antigenic drift,
Serena Marchi, Ilaria Manini, Otfried Kistner, Pietro Piu, Edmond J. Remarque, Alessandro Manenti, Fabrizio Biuso, Tommaso Carli, Giacomo Lazzeri, Emanuele Montomoli, Claudia Maria Trombetta   +10 more
doaj   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Harnessing the potential of blood donation archives for influenza surveillance and control.

PLoS ONE, 2020
Many blood donation services around the globe maintain large archives of serum and/or plasma specimens of blood donations which could potentially be used for serologic surveillance and risk assessment of influenza.
Yanyu Zhang, Kathy Leung, Ranawaka A P M Perera, Cheuk-Kwong Lee, J S Malik Peiris, Joseph T Wu   +5 more
doaj   +1 more source

استانداردسازی الایزا برای ردیابی پادتن ویروس برونشیت عفونی [PDF]

Archives of Razi Institute, 2005
An indirect enzyme–linked immunosorbent assay (ELISA) was developed for screening of antibody to avian infectious bronchitis virus (IBV). Antigen was prepared from whole-purified IBV Massachusetts serotype (BR 801 strain).
هادی قدکچی, ح. دادرس, سیدعلی پوربخش, سیدمحمدحسین حسینی   +3 more
doaj   +1 more source

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

Wildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie, Luyao Wang, Mengna Chen, Qinjie Chang, Hongyu Jiang, Haitao Xu, Liu Dan, Xiang Li, Yulong Wang, Xiangwei Zeng, Bin Yang, Miaowei Wang, Yonggang Jiang, Hongliang Chai, Siyuan Yang, Yajun Wang   +15 more
wiley   +1 more source

Preparation of avian influenza H5N1 and Newcastle disease antigens for hemagglutination inhibition assay applications

Current Biomedicine
Background Avian influenza (AI) and Newcastle disease (ND) are major poultry diseases in Indonesia, where monitoring of vaccination efficacy commonly relies on the hemagglutination inhibition (HI) assay.
Okti Nadia Poetri, Syaharani Salsabila, Nada Adinda Pebriana   +2 more
doaj   +1 more source