Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley +1 more source
7‐O‐, 9‐O‐, and 7,9‐di‐O‐acetylated GD3 gangliosides can be prepared by chemical assembly of a tetrasaccharide as α‐glycosyl fluoride that is coupled to sphingosine using a glycosynthase, followed by O‐acetyl editing by coronaviral hemagglutinin‐esterases (HEs).
Zhiyong Zhang +5 more
wiley +2 more sources
Ampicillin/Sulbactam-induced Hemolytic Anemia Manifested as Hyperbilirubinemia in a Preterm Infant [PDF]
A female was born at 36+5 weeks of gestation with a birth weight of 2,120 g. Apgar score was 7 at 1 minute and 9 at 5 minutes. Shortly after birth, tachypnea, chest retraction, and a severe build-up of oral secretions were noted.
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Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Choosing polymer microspheres for carrying out the latex agglutination reaction in plates
Serological tests based on an agglutination reaction are commonly applied in clinical laboratories for the diagnosis of various infectious diseases. There is a wide selection of microsphere-based diagnostic agglutination tests (yes/no results) and assays
E. V. Volkova +5 more
doaj
Aquarium dermatitis: Cercarial dermatitis in an aquarist [PDF]
A 33-year-old man presented with very itchy red papules on the back of his hands and forearms. These papules appeared about 90 min after he had cleaned his aquarium in which he kept native fish and watersnails.
Bastert, J. +3 more
core +1 more source
The Americanization of Nigerian English spelling and punctuation
Abstract Spelling is the most standardized level of language, and prescriptive spelling norms in former British colonies often advocate adherence to British spelling norms which differs from the local linguistic reality. Hence, recent research on the evolution of postcolonial Englishes and the Americanization of Englishes worldwide has questioned the ...
Temitayo Olatoye
wiley +1 more source
The application of PCR based methods in diagnostics of some viral infections of swine [PDF]
Viral infections of swine cause significant economic losses in swine husbandry. They manifest in death of infected animals of different ages or in decreased productivity during the manufacturing process.
Nišavić Jakov +4 more
doaj
Prova de hemaglutinação passiva para a evidenciação da toxina do C. diphtherias na lesão diftérica
Foi demonstrada a presença da toxina do C. diphtheriae, através de prova de hemaglutinação passiva, usando-se hemácias sensibilizadas com antitoxina diftérica, na lesão da garganta de 47,7% dos casos suspeitos de difteria examinados no presente trabalho.
Dacio de Almeida Christovão +2 more
doaj +1 more source
Organization of aerobactin, hemolysin, and antibacterial resistance genes in lactose negative Escherichia coli strains of serotype O4 isolated from children with dhiarrea [PDF]
Epidemiologically related, non-lactose-fermenting (NLF) Escherichia coli strains of serotype O4 have been isolated at a high frequency from children with diarrhea in Somalia (M. Nicoletti, F. Superti, C. Conti, A. Calconi, and C. Zagaglia, J.
Calconi, Attilio +5 more
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