Mechanism of Interaction Between Lung Surfactant Protein-D and Influenza A Virus Hemagglutinin [PDF]
Boon Chong Goh +4 more
openalex +1 more source
Abstract Palmitoylation is a reversible post‐translational modification that enhances protein hydrophobicity and regulates cellular functions such as trafficking and signaling. In humans, this modification is catalyzed by 23 DHHC enzymes, but the mechanisms by which they recognize their substrates remain unclear.
Dina A. Abdulrahman, Michael Veit
wiley +1 more source
Characterization of Protein Involved in Hemolysis Expressed by Sneathia amnii, a Pathogen of the Female Urogenital Tract [PDF]
Sneathia amnii is a poorly characterized gram-negative anaerobe that commonly colonizes the vagina. It has been linked to many obstetric disorders, including preterm labor, preeclampsia, and chorioamnionitis. S.
Carrasco, Lizette +3 more
core +1 more source
Advances in Therapeutic Antibody Discovery and Development Targeting G Protein‐Coupled Receptors
ABSTRACT G protein‐coupled receptors (GPCRs) are integral to numerous biological processes and are associated with various diseases across all therapeutic areas. Consequently, GPCRs present substantial potential for antibody‐based therapies. This review offers an overview of the therapeutic GPCR‐antibody target landscape and examines the diversity ...
Catherine J. Hutchings +6 more
wiley +1 more source
The short-lived MATα2 transcriptional regulator is ubiquitinated in vivo [PDF]
The substrates of ubiquitin-dependent proteolytic pathways include both damaged or otherwise abnormal proteins and undamaged proteins that are naturally short-lived. Few specific examples of the latter class have been identified, however.
Chau, Vincent +3 more
core
Influenza A virus hemagglutinin remodels membranes into a vRNP clustering platform [PDF]
Petr Chlanda +5 more
openalex +1 more source
Hydroxypropyl Cellulose Enhances Immune Responses to the Current Seasonal Influenza Vaccine in Mice
ABSTRACT Influenza A and B viruses cause annual epidemics and continue to pose global public health concerns. The most effective approach to preventing or mitigating the severity of influenza is vaccination. Inactivated split influenza HA vaccines are commonly used worldwide due to their strong safety profile and broad range of target groups; however ...
Nantaporn Kaewaroon +4 more
wiley +1 more source
Structure of a Complex of the Human α/β T Cell Receptor (TCR) HA1.7, Influenza Hemagglutinin Peptide, and Major Histocompatibility Complex Class II Molecule, HLA-DR4 (DRA0101 and DRB10401) [PDF]
Jens Hennecke, Don C. Wiley
openalex +1 more source
Abstract The currently circulating high‐pathogenicity avian influenza (HPAI) virus of the subtype H5 causes variable illness and death in wild and domestic birds and mammals, as well as in humans. This virus evolved from the Goose/Guangdong lineage of the HPAI H5 virus, which emerged in commercial poultry in China in 1996, spilled over into wild birds,
Thijs Kuiken +9 more
wiley +1 more source

