Results 131 to 140 of about 136,940 (248)
A Genetic Reporter for Visualizing Nitroreductase Activity Using Magnetic Resonance Imaging
We introduce a reporter gene technology to noninvasively visualize bacterial nitroreductase activity. Our method utilizes a magnetic resonance imaging (MRI) reporter based on aquaporin, which is fused to a destabilizing domain, resulting in their degradation (off‐state).
Jinyang Wan +4 more
wiley +1 more source
Detection of low‐abundance proteins at the point‐of‐care is key for early detection and real‐time monitoring. The clinical translation of such assays is hindered by biofouling, matrix variability, and signal instability. RT‐MagMAp assay overcomes these challenges and enables precise protein quantification in human plasma using a hierarchical assembly ...
Payel Sen +8 more
wiley +2 more sources
Stability of rubella hemagglutinin [PDF]
R R, Rafajko +3 more
openaire +2 more sources
ConforFold recovers alternative protein conformations beyond MSA subsampling
Abstract Conformational changes underlie many aspects of protein function, yet current structure prediction tools remain limited in their ability to systematically sample structural ensembles. Here, we present ConforPSSP and ConforFold, a combined framework that integrates secondary‐structure sampling into a deep learning‐based prediction to recover ...
Raulia Syrlybaeva, Eva‐Maria Strauch
wiley +1 more source
SARS‐CoV‐2 Variants and Immune Evasion: Mapping the Future of Vaccine Design
ABSTRACT The evolutionary trajectory of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) has progressed through several distinct phases since its zoonotic emergence, transitioning from initial human adaptation to an era of rapid antigenic drift and complex immune evasion. As of early 2026, the global landscape is dominated by highly evolved
Fatih Uzer +2 more
wiley +1 more source
This review displays a comprehensive overview of glanders, including aetiology, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs. It has also reviewed differential diagnosis and treatment both in animals and humans as well as organism's antimicrobial properties.
Yahya Kanani +2 more
wiley +1 more source
Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers +16 more
wiley +1 more source
Gamma‐irradiated Newcastle disease virus: an alternative inactivated oncolytic virotherapy
To overcome biological risks associated with using live NDV as an oncolytic therapy, we developed gamma‐NDV as a safer alternative. Using a murine model for skin cancer, we show that intratumor administration of gamma‐NDV outperformed live‐NDV in terms of reducing tumor growth and improving overall animal survival. Abstract Newcastle disease virus (NDV)
Eve V Kennedy +10 more
wiley +1 more source
ABSTRACT The 2024/2025 influenza season in Italy was characterised by cocirculation of influenza A and B viruses. Monitoring influenza vaccine effectiveness (IVE) remains essential to guide public health policy due to antigenic shifts and varying strain circulation.
Daniel Cifo +12 more
wiley +1 more source
ABSTRACT Introduction Influenza A viruses (IAVs) are responsible for respiratory infections in a wide range of species, including birds, swine and humans. The role of wild boar (Sus scrofa) in IAV epidemiology remains underexplored. Here, we present a longitudinal serologic and virologic surveillance study of wild boars in Spain from 2015 to 2023 ...
Paloma Encinas +8 more
wiley +1 more source

