Results 111 to 120 of about 90,526 (229)
ABSTRACT Influenza viruses cause seasonal epidemics, and current vaccines do not fully protect against them. This study focuses on long non‐coding RNAs (lncRNAs), which are RNA molecules that do not code for proteins but play crucial roles in various biological processes. We identified 17 lncRNAs altered by the influenza virus.
Samuel Pushparaj +9 more
wiley +1 more source
Clinical Course, Viral Load, and (Sub)Type of Influenza in Hospitalized Children in Southern Germany
ABSTRACT This study aimed to assess the relationship between clinical course and influenza virus characteristics by quantifying viral load and performing phylogenetic analyses in hospitalized children. Children aged 0–3 years presenting with an acute respiratory tract infection (RTI) at the Childrens' Hospital Heidelberg/Germany were included and ...
Sarah Klemm +9 more
wiley +1 more source
Bio‐derived lignin–Eosin Y macromolecular networks are developed as visible‐light‐responsive self‐sterilizing coatings that generate reactive oxygen species without leaching. The spray‐coated photopolymerized surfaces exhibit durable antibacterial and antiviral activity under ambient light for extended periods, demonstrating a scalable and sustainable ...
Euna Oh +7 more
wiley +1 more source
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang +3 more
wiley +1 more source
Lysine acetyltransferase 2A (KAT2A) is a transcriptional coactivator and a member of the Histone Acetyltransferase (HAT) family. While altered KAT2A activity has been implicated in various cancers, its role in bladder cancer (BLCA) remains poorly understood.
Wenjie Yang +8 more
wiley +1 more source
ABSTRACT Preexisting immunity to influenza confers rapid protection against antigenically matched viruses but can also constrain responses to drifted variants. This review asks when and why prior infection or vaccination is protective versus detrimental, and which biological mechanisms—epitope masking by circulating antibody, inhibitory FcγRIIb ...
Annette Fox +2 more
wiley +1 more source
Immunogenicity and safety of AS03-adjuvanted A/Astrakhan/3212/2020 (H5N8)-like influenza vaccine in adults: Phase 1/2, observer-blinded, randomized trial. [PDF]
Hastie A +6 more
europepmc +1 more source
Counteracting Influenza Virus Evolution Through the Full Spectrum of Broadly Protective Antibodies
ABSTRACT Despite the presence of licensed vaccines and therapeutics, influenza viruses remain a major public health concern, as they cause seasonal respiratory infections and pose a pandemic threat through the emergence of zoonotic strains. Although neutralizing antibodies elicited by seasonal vaccination constitute a primary defense against infection,
Yu Adachi, Yoshimasa Takahashi
wiley +1 more source
SPCE-Based Electrochemical Immunosensor for Influenza A (H1) Detection in Serum and Nasopharyngeal Samples. [PDF]
Garza-Villegas MD +6 more
europepmc +1 more source
GC B Cells, Tfh Cells, and Influenza bnAbs: Insights for Improving Universal Vaccine Design
ABSTRACT Antibodies are crucial for providing protection against influenza virus infection; however, protective humoral immunity is limited by antigenic drift and shift. Hence, the discovery of broadly neutralizing antibodies (bnAbs) targeting conserved epitopes on hemagglutinin protein evokes the hope of developing a universal influenza vaccine ...
Takeshi Inoue +2 more
wiley +1 more source

