Results 91 to 100 of about 108,411 (200)

How Much Bean Hemagglutinin Is Safe for Human Consumption?

, 2018
How Much Bean Hemagglutinin Is Safe for Human ...
Alireza Abbaspourrad (1305903), Zhong Zhang (103242)   +1 more
core   +1 more source

Genotype‐Informed Whole‐Animal Kinome Screening Reveals Shared Kinase Vulnerabilities Across Driver Contexts in PDAC

Cancer Science, EarlyView.
Overview of experimental workflow and key findings. Clinically prevalent 2‐hit and 3‐hit PDAC genotypes were first modeled in Drosophila to enable kinome‐wide genetic screening. Candidate therapeutic targets were prioritized using human tumor expression data and pathway enrichment analyses.
Han Hai, Takako Ooshio, Hui Jiang, Taku Kimura, Yusuke Satoh, Soichiro Hata, Taiga Hirata, Jiayi Liu, Tongwei Liu, Ryodai Yamamura, Masahiro Sonoshita   +10 more
wiley   +1 more source

Influence of elastin-like polypeptide and hydrophobin on recombinant hemagglutinin accumulations in transgenic tobacco plants. [PDF]

, 2014
Fusion protein strategies are useful tools to enhance expression and to support the development of purification technologies. The capacity of fusion protein strategies to enhance expression was explored in tobacco leaves and seeds.
Trong Phan, Hoang, Phan, Hoang Trong, Joensuu, Jussi, Gerd Hause, Hause, Gerd, Bettina Hause, Arcalis, Elsa, Hoang Trong Phan, Friedrich Altmann, Jussi Joensuu, Elsa Arcalis (575720), Daniel Maresch, Altmann, Friedrich, Eva Stoger, Udo Conrad, Bettina Hause (52316), Friedrich Altmann (33138), Conrad, Udo, Udo Conrad (575723), Daniel Maresch (575722), Eva Stoger (575721), Elsa Arcalis, Maresch, Daniel, Hause, Bettina, Gerd Hause (236755), Hoang Trong Phan (575719), Stoger, Eva, Jussi Joensuu (145616), Phan Hoang Trong, Stoger Eva, Maresch Daniel, Joensuu Jussi, Arcalis Elsa, Altmann Friedrich, Hause Bettina, Hause Gerd, Conrad Udo   +36 more
core   +1 more source

Simultaneous modification of Thermotoga maritima encapsulin subunits to produce multivalent nanoparticle vaccines for non‐typhoidal Salmonella enterica

The FEBS Journal, EarlyView.
This study investigates the modularity of encapsulin—a protein nanoparticle—by simultaneously inserting up to four distinct Salmonella epitopes within the encapsulin subunit. The encapsulin variants were transiently expressed in plants where they assembled into nanoparticles; however, their accumulation and stability varied depending on the ...
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +5 more
wiley   +1 more source

The lowest energy conformation of CL-385319-hemagglutinin complex.

, 2012
The lowest energy conformation of CL-385319-hemagglutinin complex.
Zhibo Zhu (146697), Shuwen Liu (146709), Runming Li (146682), Deshou Song (146688), Hanhong Xu (146703)   +4 more
core   +1 more source

Discovery of Pentacyclic Triterpenoid PROTACs as a Class of Effective Hemagglutinin Protein Degraders

, 2022
Influenza hemagglutinin that drives viral entry into cells via the membrane fusion process is an up-and-coming antiviral drug target. Herein, we described for the first time the design, synthesis, and biological characteristics of a new class of ...
Shouxin Wang (2235853), Lihe Zhang (665176), Sulong Xiao (1705795), Haiwei Li (282229), Wenxiao Ma (1694977), Yanliang Yi (12022778), Xinyuan Ma (5262572), Boyang Cheng (11465649), Demin Zhou (268636)   +8 more
core   +1 more source

Variable Infection Outcomes in Repeated Experimental Challenges of Atlantic Salmon (Salmo salar) With an Infectious Salmon Anaemia Virus Isolate

Journal of Fish Diseases, EarlyView.
ABSTRACT Infectious salmon anaemia (ISA) affects Atlantic salmon (Salmo salar) and is caused by the ISA virus (ISAV). The disease is associated with ISAV strains with deletions in the hemagglutinin‐esterase protein, named HPRΔ variants. The present study was initially designed as a vaccine efficacy study against ISA.
Lars Ole Sti Dahl, Stine Braaen, Øystein Wessel, Johanna Hol Fosse, Espen Rimstad   +4 more
wiley   +1 more source

Multiple Sequence Alignment of Influenza Hemagglutinin Protein Sequences

, 2013
The NCBI influenza virus resource was used to download 11,981 full-length, non-redundant Influenza hemagglutinin protein sequences (August 2011). Homologs were aligned using MUSCLE and saved in MSF format. Sequence names formatted for use by JProfileGrid
Alberto Roca (98662)
core   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Differential ubiquitin modifications of ESCRT‐I subunits VPS37‐1 and VPS28‐2 positively regulate plant immunity

New Phytologist, EarlyView.
The RING type ubiquitin ligase (E3), XBAT35.2, positively regulates FLS2‐mediated plant immunity against bacterial pathogens by modifying the ESCRT‐I subunits VPS28‐2 and VPS37‐1 with distinct ubiquitin chain types. Summary Sensing of pathogen‐associated molecular patterns (PAMPs) by pattern recognition receptors at the cell surface initiates the first
Chaofeng Wang, Yi Zhang, Bangjun Zhou, Pooja Verma, Lirong Zeng   +4 more
wiley   +1 more source