Results 81 to 90 of about 102,208 (283)

Protective Efficacy of Recombinant Influenza Hemagglutinin Ectodomain Fusions [PDF]

, 2021
In current seasonal influenza vaccines, neutralizing antibody titers directed against the hemagglutinin surface protein are the primary correlate of protection. These vaccines are, therefore, quantitated in terms of their hemagglutinin content.
Raju S. Rajmani, Xavier Saelens, Malladi, Sameer Kumar, Madhuraj Bhat, Raghavan Varadarajan, Mittal, Nidhi, Rajmani, Raju S., Nidhi Mittal, Sameer Kumar Malladi, Nayanika Sengupta, Sedeyn, Koen, Reddy, Poorvi, Varadarajan, Raghavan, Sengupta, Nayanika, Somnath Dutta, Saelens, Xavier, Bhat, Madhuraj, Koen Sedeyn, Poorvi Reddy, Dutta, Somnath   +19 more
core   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Hemagglutinin Activities in Pearl Oyster, Pinctada fucata martensii, Hemolymph [PDF]

, 1988
Occurrence and partial characterization of hemagglutinin activities in the pearl oyster, Pinctada fucata martensii, hemolymph were investigated. Comparison of natural hemagglutinin activities against various kinds of erythrocytes (Table 1) revealed a ...
森, ,勝義, モリ, カツヨシ, Mori, Katsuyoshi, 山口, 一登, ヤマグチ, カズト, Yamaguchi, Kazuto, 3286, 4248   +7 more
core  

hemagglutinin trees NC/SC/OT xml [PDF]

, 2014
hemagglutinin trees NC/SC/OT ...
Trevor Bedford (376961), Robert J. Woods (175743), Mercedes Pascual (19597), Edward B. Baskerville (189872), Zinder, Daniel, Baskerville, Edward B., Woods, Robert J., Roy, Manojit, Manojit Roy (104218), Bedford, Trevor, Pascual, Mercedes, Daniel Zinder (106377)   +11 more
core   +1 more source

Synthetic DNA co-immunization with vaccine-aligned common consensus nucleoprotein and hemagglutinin protects mice against lethal influenza infection with a single immunization

Frontiers in Immunology
IntroductionThere is an urgent need for influenza vaccine strategies that enhance protection against influenza virus drift and across different subtypes. The conserved viral nucleoprotein (NP) is the most abundant viral protein during replication, and a
Ebony N. Gary, Abigail R. Trachtman, Dan Wang, Suman Bharti, Ying Ye, Nicholas J. Tursi, Nicholas J. Tursi, Martina Tomirotti, Martina Tomirotti, Jillian Eisenhauer, Jillian Eisenhauer, Jacqueline D. Chu, David Custodio Zegarra, Casey E. Hojecki, Micki Zheng, Micki Zheng, Jayamanna Wickramasinghe, David B. Weiner, Ami Patel   +18 more
doaj   +1 more source

Hemagglutinins in Sera of Africans of Gambia

Experimental Biology and Medicine, 1968
SummaryThirty-eight sera from Africans of Gambia were studied serologically. Twenty-two sera had increased titers of agglutinins to guinea pig erythrocytes and 20 had increased titers of rat hemagglutinins. Of 19 individuals of blood group O, 9 had increased titers of agglutinins to human A and/or B erythrocytes.
K, Kano, I A, McGregor, F, Milgrom
openaire   +2 more sources

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Summary of hemagglutinin inhibition (HI) titres. [PDF]

, 2014
Summary of hemagglutinin inhibition (HI) titres.
Martin Gilbert (137251), Björn F. Koel (674883), Theo M. Bestebroer (327455), Derek J. Smith (247972), Nicola S. Lewis (389210), Ron A. M. Fouchier (169412)   +5 more
core   +1 more source

Stability of vaccine strains of seasonal live attenuated influenza vaccines when adapted to MDCK cell culture

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Currently, the vast majority of influenza vaccines in the world are produced using developing chicken embryos as substrate, but there is an urgent necessity for transferring vaccine production to continuous cell lines, which would ensure ...
Victoria A. Matyushenko, Arina D. Kostromitina, Ekaterina A. Stepanova, Larisa G. Rudenko, Irina N. Isakova-Sivak   +4 more
doaj   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source