Results 91 to 100 of about 21,210 (213)

Fusion pore conductance to determine the effects of mutating the structure of influenza virus hemagglutinin [PDF]

, 2016
Enveloped viruses, such as influenza, infect cells by fusing their viral envelope with the cell membrane. The fusion pore is a macromolecular structure that links two membranes that are fusing.
Wachter, Rebecca
core   +1 more source

Multiplex evaluation of influenza neutralizing antibodies with potential applicability to in-field serological studies [PDF]

, 2014
The increased number of outbreaks of H5 and H7 LPAI and HPAI viruses in poultry has major public and animal health implications. The continuous rapid evolution of these subtypes and the emergence of new variants influence the ability to undertake ...
Cattoli, G., Cattoli, G., Molesti, E., Molesti, E., Rahman, R., Rahman, R., Temperton, N.J., Temperton, N.J., Terregino, C., Terregino, C., Wright, E., Wright, E.   +11 more
core   +6 more sources

Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation

Small, Volume 22, Issue 15, 12 March 2026.
Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Anke Schmidt, Meike Heuser, Paul Schulan, Lea Miebach, Alice Martinet, Marcus Frank, Kristian Wende, Sander Bekeschus   +7 more
wiley   +1 more source

Avian influenza A (H9N2): computational molecular analysis and phylogenetic characterization of viral surface proteins isolated between 1997 and 2009 from the human population [PDF]

, 2010
Background H9N2 avian influenza A viruses have become panzootic in Eurasia over the last decade and have caused several human infections in Asia since 1998.
Azeem M Butt, Samerene Siddique, Muhammad Idrees, Yigang Tong   +3 more
core   +2 more sources

Lock, Protect, and Bind: In Vitro Selection of Locked Nucleic Acid‐Modified Aptamers Using a Mutant T7 RNA Polymerase

Small Structures, Volume 7, Issue 3, March 2026.
We present a novel approach for co‐transcriptional incorporation of locked nucleic acid (LNA) and 2′‐fluoro (2′F) modifications using a mutant T7 RNA polymerase. This method is compatible with in vitro selection and enables efficient, primer‐independent synthesis and amplification of LNA‐modified RNA aptamers with enhanced stability, targeting ...
Kevin Neis, Laia Civit, Kathrine Pedersen, Michael Schachtner, Jesper Wengel, Ralf Wagner, Steffen Thiel, Jørgen Kjems, Julián Valero   +8 more
wiley   +1 more source

Structural intermediates in the low pH-induced transition of influenza hemagglutinin.

PLoS Pathogens, 2020
The hemagglutinin (HA) glycoproteins of influenza viruses play a key role in binding host cell receptors and in mediating virus-host cell membrane fusion during virus infection.
Jingjing Gao, Miao Gui, Ye Xiang
doaj   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, Volume 293, Issue 6, Page 1587-1611, March 2026.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

The production and development of H7 Influenza virus pseudotypes for the study of humoral responses against avian viruses [PDF]

, 2013
In recent years, high pathogenicity avian influenza (HPAI) virus, H5N1, low pathogenicity avian influenza (LPAI) virus, H9N2, and both HPAI and LPAI H7 viruses have proved devastating for the affected economies reliant on poultry industry, and have posed
Böttcher-Frieberthäuser, Eva, Cattoli, Giovanni, Ferrara, Francesca, Molesti, Eleonora, Temperton, Nigel, Terregino, Calogero   +5 more
core   +3 more sources

Correction: An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism

PLOS Pathogens, 2016
Influenza viruses cause seasonal flu each year and pandemics or epidemic sporadically, posing a major threat to public health. Recently, a new influenza D virus (IDV) was isolated from pigs and cattle. Here, we reveal that the IDV utilizes 9-O-acetylated sialic acids as its receptor for virus entry.
Song, Hao, Qi, Jianxun, Khedri, Zahra, Diaz, Sandra, Yu, Hai, Chen, Xi, Varki, Ajit, Shi, Yi, Gao, George F   +8 more
openaire   +5 more sources

Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe, Tamara Zoran, Marylyn Martina Addo   +2 more
wiley   +1 more source