Results 101 to 110 of about 23,124 (216)

Antigenic Characterization of H1N1 Influenza Viruses That Circulated During the 2019–2020 Season in Philadelphia, Pennsylvania

Influenza and Other Respiratory Viruses, Volume 19, Issue 6, June 2025.
ABSTRACT Background Multiple clades of H1N1 influenza A viruses (IAVs) circulated during the 2019–2020 season. Here, we completed serological assays to determine the specificities of serum antibodies from humans infected with viruses from different H1N1 clades during the 2019–2020 season.
Lydia M. Mendoza, Elizabeth M. Anderson, Ashley Sobel Leonard, Alexander G. McFarland, Jordan T. Ort, Nicole Tanenbaum, Afeesat Durosinmi, Frederic D. Bushman, Laurel J. Glaser, Irving Nachamkin, Scott E. Hensley   +10 more
wiley   +1 more source

Punctuated evolution of influenza virus hemagglutinin (A/H1N1) under opposing migration and vaccination pressures [PDF]

arXiv, 2012
Influenza virus contains two highly variable envelope glycoproteins, hemagglutinin (HA) and neuraminidase (NA). The structure and properties of HA, which is responsible for binding the virus to the cell that is being infected, change significantly when the virus is transmitted from avian or swine species to humans. Previously we identified much smaller
arxiv  

The role of influenza neuraminidase transmembrane domain on budding and virus morphology [PDF]

, 2014
Influenza A virus neuraminidase (NA), a type II transmembrane glycoprotein plays a role in the cleavage of sialic acids and facilitating the release of mature virions from the surface of infected cells. NA has also previously been shown to play a role in
Roddy, Scott, Edward
core  

Vaccination with DNA plasmids expressing Gn coupled to C3d or alphavirus replicons expressing Gn protects mice against rift valley fever virus [PDF]

, 2010
Background: Rift Valley fever (RVF) is an arthropod-borne viral zoonosis. Rift Valley fever virus (RVFV) is an important biological threat with the potential to spread to new susceptible areas. In addition, it is a potential biowarfare agent. Methodology/
A Jouan, A Zaki, B Botros, BH Bird, BS Peters, CS Schmaljohn, CS Schmaljohn, Daniel G. Bausch, DB Wallace, DV Lim, FR Toapanta, FR Toapanta, G Lorenzo, GF Meadors 3rd, H Caplen, I Watanabe, J Lubroth, J Meegan, J Naslund, J Naslund, JA Mitchell, JF Bower, JF Bower, JR Haynes, JT van Oirschot, K Keegan, K Spik, KA Hubbard, M Mkrtichyan, MA Kutzler, Mark T. Heise, MT Heise, N Lagerqvist, Nitin Bhardwaj, P Hunter, P Jansen van Vuren, P Nguku, P Pittman, P Pushko, P Vialat, PR Pittman, PW Dempsey, R Gorchakov, R Gorchakov, R Randall, RJ Daubney, S Won, SA Kamal, SR Gerrard, SR Gerrard, T Shoemaker, TA Madani, TD Green, Ted M. Ross, TM Pertmer, TM Pertmer, TM Ross, TM Ross, UB Balasuriya   +58 more
core   +4 more sources

Passive Immunization in the Prevention and Treatment of Viral Infections

European Journal of Immunology, Volume 55, Issue 5, May 2025.
The development of new technologies for generating monoclonal antibodies has made it possible to extend the use of monoclonal antibodies for controlling viral infections. Here, we discuss the advances in antibody cloning techniques and the current use of passive immunization both as a preventative measure and treatment of viral infection.
Romila Moirangthem, Yotam Bar‐On
wiley   +1 more source

Punctuated evolution of influenza virus neuraminidase (A/H1N1) under migration and vaccination pressures [PDF]

arXiv, 2012
Influenza virus contains two highly variable envelope glycoproteins, hemagglutinin (HA) and neuraminidase (NA). The structure and properties of HA, which is responsible for binding the virus to the cell that is being infected, change significantly when the virus is transmitted from avian or swine species to humans.
arxiv  

Oligomerization, Secretion, and Biological Function of an Anchor-Free Parainfluenza Virus Type 2 (PI2) Fusion Protein [PDF]

, 2000
A number of studies indicate that the transmembrane domain, the cytoplasmic domain, or both regions of viral surface glycoproteins are involved in quaternary structure formation.
Compans, Richard W., Tong, Suxiang
core   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source

Entry Inhibition of Influenza Viruses with High Mannose Binding Lectin ESA-2 from the Red Alga Eucheuma serra through the Recognition of Viral Hemagglutinin

Marine Drugs, 2015
Lectin sensitivity of the recent pandemic influenza A virus (H1N1-2009) was screened for 12 lectins with various carbohydrate specificity by a neutral red dye uptake assay with MDCK cells.
Yuichiro Sato, Kinjiro Morimoto, Takanori Kubo, Takemasa Sakaguchi, Akira Nishizono, Makoto Hirayama, Kanji Hori   +6 more
doaj   +1 more source

Tropical neural networks and its applications to classifying phylogenetic trees [PDF]

arXiv, 2023
Deep neural networks show great success when input vectors are in an Euclidean space. However, those classical neural networks show a poor performance when inputs are phylogenetic trees, which can be written as vectors in the tropical projective torus. Here we propose tropical embedding to transform a vector in the tropical projective torus to a vector
arxiv