A modular platform to display multiple hemagglutinin subtypes on a single immunogen. [PDF]
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Phylogenetic and Mutation Analysis of Hemagglutinin Gene from Highly Pathogenic Avian Influenza Virus H5 Clade 2.3.4.4b in South America. [PDF]
Bruno A +3 more
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H128N Substitution in the Sa Antigenic Site of HA1 Causes Antigenic Drift Between Eurasian Avian-like H1N1 and 2009 Pandemic H1N1 Influenza Viruses. [PDF]
Meng F +12 more
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Broad-Spectrum Virucidal Activity of Nitric Oxide Nasal Spray (NONS) Against SARS-CoV-2 Variants and Major Respiratory Viruses. [PDF]
Martins J +3 more
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Characterization of the glycoproteins of fish and amphibian influenza B-like viruses. [PDF]
Singh G +10 more
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Characterization of two non-competing antibodies to influenza H3N2 hemagglutinin stem reveals its evolving antigenicity. [PDF]
Gopal AB +9 more
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Hybrid Adjuvant-Allergen H1sD2 Proteoforms Enhance Innate Immunity Activation via Distinct N-Glycosylation Profiles. [PDF]
Lopandić Z +5 more
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TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus
Journal of Virology, 2021Influenza C virus (ICV) is a pathogen that causes acute respiratory illness, mostly in children, but there are no anti-ICV drugs. ICV has only one kind of spike protein, the hemagglutinin-esterase (HE) glycoprotein on the virion surface, which possesses receptor-binding, receptor-destroying, and membrane fusion activities.
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Fusion mutants of the influenza virus hemagglutinin glycoprotein
Cell, 1985The influenza virus hemagglutinin (HA) mediates viral entry into cells by a low pH induced membrane-fusion event in endosomal vesicles. Mutant viruses with altered pH dependence for both hemolysis and the HA conformational change required for fusion were selected for their ability to grow in cells treated with amantadine hydrochloride, which raises the
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