High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains. [PDF]
Kikawa C +12 more
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Genetic and Serological Analysis of H7N3 Avian Influenza Viruses in Mexico for Pandemic Risk Assessment. [PDF]
Ayora-Talavera G +8 more
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The Elicitation of an Antigen-Specific Antibody Immune Response Using a Nanoparticulate Adjuvant Derived from <i>Saponaria officinalis</i>. [PDF]
Bogoyavlenskiy A +7 more
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Differences in Glycoproteins and the Potential for Early Protection Using LAIV Based on Drift Variants of the A/H1N1pdm09 Influenza Virus. [PDF]
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Influenza A(H3N2) subclade K (J.2.4.1) viruses associated with a surge at a university health clinic, Arizona, the United States, November to early December 2025. [PDF]
Scotch M +7 more
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HA Protein acetylation modulates replication, pathogenicity, and immunogenicity of influenza virus and facilitates live-attenuated vaccine design. [PDF]
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TMPRSS2 Activates Hemagglutinin-Esterase Glycoprotein of Influenza C Virus
Journal of Virology, 2021Influenza C virus (ICV) is a pathogen that causes acute respiratory illness, mostly in children, but there are no anti-ICV drugs. ICV has only one kind of spike protein, the hemagglutinin-esterase (HE) glycoprotein on the virion surface, which possesses receptor-binding, receptor-destroying, and membrane fusion activities.
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Fusion mutants of the influenza virus hemagglutinin glycoprotein
Cell, 1985The influenza virus hemagglutinin (HA) mediates viral entry into cells by a low pH induced membrane-fusion event in endosomal vesicles. Mutant viruses with altered pH dependence for both hemolysis and the HA conformational change required for fusion were selected for their ability to grow in cells treated with amantadine hydrochloride, which raises the
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Membrane fusion activity of reconstituted vesicles of influenza virus hemagglutinin glycoproteins
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1983Reconstituted vesicles of hemagglutinin glycoproteins into egg yolk phosphatidylcholine/spin-labeled phosphatidylcholine/cholesterol (molar ratio 1.6:0.4:1) were prepared by dialysis. Preparations at appropriate protein-to-lipid ratios (1:44 and 1:105 mol/mol) contained vesicles with a diameter of 100-300 nm and a high density of spikes on the surface.
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