Results 161 to 170 of about 1,825 (196)
Flow cytometric analysis of erythroid precursors and mutational signatures of lower risk myelodysplastic syndromes identify responders to erythroid stimulating agents. [PDF]
Blood Cancer JRaddi MG +17 more
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Journal of Urology, 1991
We report 2 cases of nephrolithiasis owing to hematin stones. One patient had no apparent explanation for this finding, while the other was receiving warfarin anticoagulation for a prosthetic aortic valve. The chemical nature, etiology and clinical features of hematin calculi are discussed.
Jeffrey I. Miller +2 more
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We report 2 cases of nephrolithiasis owing to hematin stones. One patient had no apparent explanation for this finding, while the other was receiving warfarin anticoagulation for a prosthetic aortic valve. The chemical nature, etiology and clinical features of hematin calculi are discussed.
Jeffrey I. Miller +2 more
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Hematin therapy in porphyric attacks
Klinische Wochenschrift, 1980We report our experience with hematin in the treatment of 57 patients in porphyric attacks. The ratio of acute intermittent porphyria: variegate porphyria: hereditary coproporphyria was 43:11:3. More than 90% of the patients showed not only a decline in their porphyrin precursors, but also a favor able clinical response.
Claus A. Pierach +4 more
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Investigations of B- and β-hematin
Journal of Inorganic Biochemistry, 1997The preparation from ferriprotoporphyrin IX (FP) in aqueous acid medium of the related pigments beta- and B-hematin [see G. Blauer and M. Akkawi, Biochem. Mol. Biol. Int. 35, 231 (1995)] is presented under different conditions. Both pigments are characterized by infrared spectra which differ in the range of 1600-1700 cm-1 in their strong bands with ...
M. Akkawi, G. Blauer
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Hematin Anhydride (Β-Hematin): An Analogue to Malaria Pigment Hemozoin Possesses Nonlinearity
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023Hematin anhydride (β-hematin), the synthetic analogue of the malaria pigment, "hemozoin", is a heme dimer produced by reciprocal covalent bonds among carboxylic acid groups on the protoporphyrin-IX ring and the iron atom present in the two adjacent heme molecules. Hemozoin is a disposal product formed from the digestion of hemoglobin present in the red
Priyadarshi Sahoo +4 more
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New England Journal of Medicine, 1975
The discovery that hematin represses induction of δ-aminolevulinic acid synthetase (ALA-S), the rate-limiting enzyme for hepatic porphyrin and heme synthesis,1 is central to recent studies seeking to provide a means of terminating or ameliorating the acute attack of acute intermittent porphyria, porphyria variegata or hepatic coproporphyria.
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The discovery that hematin represses induction of δ-aminolevulinic acid synthetase (ALA-S), the rate-limiting enzyme for hepatic porphyrin and heme synthesis,1 is central to recent studies seeking to provide a means of terminating or ameliorating the acute attack of acute intermittent porphyria, porphyria variegata or hepatic coproporphyria.
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Toxicology Letters, 1978
The toxicity of intravenously administered hematin (3.4 and 6 mg100 g) was investigated in rats, where an LD50 of 4.32 mg100 g was computed, with 95% confidence limits of 5.40 and 3.46 mg100 g. At toxic levels (4 mg100 g) the rats showed a drop of blood pressure, hemorrhages and renal failure, whereas lower doses were well tolerated.
D.L. Lips, P.S. Edwards, C.A. Pierach
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The toxicity of intravenously administered hematin (3.4 and 6 mg100 g) was investigated in rats, where an LD50 of 4.32 mg100 g was computed, with 95% confidence limits of 5.40 and 3.46 mg100 g. At toxic levels (4 mg100 g) the rats showed a drop of blood pressure, hemorrhages and renal failure, whereas lower doses were well tolerated.
D.L. Lips, P.S. Edwards, C.A. Pierach
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Archives of Internal Medicine, 1978
Among the numerous throw-aways that the mailman delivers to my door are advertisements from pharmaceutical companies concerning drugs and related products. I recently received a set of complimentary starter prescriptions for a certain drug for the treatment of "iron deficiency anemia and megaloblastic anemia." The drug is composed of ferrous fumarate,
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Among the numerous throw-aways that the mailman delivers to my door are advertisements from pharmaceutical companies concerning drugs and related products. I recently received a set of complimentary starter prescriptions for a certain drug for the treatment of "iron deficiency anemia and megaloblastic anemia." The drug is composed of ferrous fumarate,
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PEROXIDASE, HEMATIN, AND PEGYLATED-HEMATIN CATALYZED VINYL POLYMERIZATIONS IN WATER
Journal of Macromolecular Science, Part A, 2001Horseradish peroxidase-, hematin- and pegylated-hematin mediated polymerization of sodium styrene sulfonate and sodium acrylate in water is reported. Molecular weight and yields were influenced by the concentrations of hydrogen peroxide and initiator, 2,4-pentanedione.
Jayant Kumar +7 more
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