Results 21 to 30 of about 7,842 (116)

Dengue, chikungunya and Zika virus surveillance in blood donors in Brazil, 2019–2021

Vox Sanguinis, Volume 121, Issue 2, Page 196-201, February 2026.
Abstract Background and Objectives Arbovirus infections are a major public health concern in Brazil and an ongoing blood safety concern. Periodic outbreaks of such infections are common in the general population. This study aimed to establish the rates of dengue, chikungunya and Zika virus (DENV, CHIKV, ZIKV) RNAemia among blood donors at six public ...
Eduard Grebe, Renata Buccheri, Leilani Montalvo, Simone Kashima, Carolina Miranda, Pamela Milani, Mars Stone, Kristin Livezey, Ligia Capuani, Cecilia S. Alencar, Luiz Amorim, Paula Loureiro, Maisa Ribeiro, Allyson Guimarães da Costa, Alfredo Mendrone Jr, Michael P. Busch, Ester C. Sabino, Brian Custer, Recipient Epidemiology and Donor Evaluation Study‐IV‐Pediatric (REDS‐IV‐P) Brazil   +18 more
wiley   +1 more source

Clinical outcomes and safety in patients with lower‐risk myelodysplastic syndromes treated with imetelstat: Substudy of the phase 3 IMerge trial

British Journal of Haematology, EarlyView.
Rami S. Komrokji, Valeria Santini, Uwe Platzbecker, Koen Van Eygen, María Díez‐Campelo, Raquel de Paz, Guillermo Sanz Santillana, Sylvain Thépot, Maciej Kaźmierczak, Esther Natalie Oliva, Mikkael A. Sekeres, Pierre Fenaux, Yazan F. Madanat, Michael R. Savona, Jennifer Riggs, Sheetal Shah, Ashley L. Lennox, Qi Xia, Libo Sun, Tymara Berry, Amer M. Zeidan   +20 more
wiley   +1 more source

Exploring the synergy between telomere length and genomic complexity in CLL

British Journal of Haematology, EarlyView.
Silvia Ramos‐Campoy, Anna Puiggros, Joanna Kamaso, Helen Parker, Gian Matteo Rigolin, Claudia Haferlach, María José Larráyoz, Rosa Collado, Rocío Salgado, María José Calasanz, Laurence Etter, Alberto Valiente, Pau Abrisqueta, Francesc Bosch, Eva Gimeno, Antonio Cuneo, Florence Nguyen‐Khac, Jacqueline Schoumans, Jonathan C. Strefford, Blanca Espinet   +19 more
wiley   +1 more source

Comparability of external and internal control patients for the prospective randomized HOVON‐103 trial in older AML patients

British Journal of Haematology, Volume 208, Issue 1, Page 179-188, January 2026.
Summary Real‐world data (RWD) previously contributed to post‐marketing regulatory decision‐making, but are currently also considered as external controls to single‐arm trials. The use of RWD control data may be compromised by methodological issues, urging validation of RWD control cohorts.
Sjoerd J. F. Hermans, Jurjen Versluis, Erik D. van Werkhoven, Yvette van Norden, Jeroen J. W. M. Janssen, Gerwin A. Huls, Thomas Pabst, Dimitri A. Breems, Elizabeth Berkx, Avinash G. Dinmohamed, Peter C. Huijgens, Eric Sträng, Jesús María Hernández Rivas, Marta Sobas, Rosa Ayala Diaz, Joaquin Martinez Lopez, Klaus H. Metzeler, Torsten Haferlach, Christian Thiede, Carin A. Uyl‐de Groot, Lars Bullinger, Bob Löwenberg, Gert J. Ossenkoppele, Francesco Pignatti, Jan J. Cornelissen   +24 more
wiley   +1 more source

Analysis of Aspergillus spp. Isolates According to Temporal–Spatial, Sociodemographic, and Clinical Variables—Microsatellite Typing of Clinical and Environmental Samples of Aspergillus fumigatus in a University Hospital in Sao Paulo, Brazil

Mycoses, Volume 69, Issue 1, January 2026.
ABSTRACT Background Typing Aspergillus species is crucial for understanding the sources of infection in hospital environments. Objectives This study analysed clinical and air samples as well as their relationship with the clinical forms of aspergillosis.
Claudia de Abreu Fonseca, Ricardo Araujo, Vivian Caso Coelho, Carlos Henrique Camargo, Marcello Mihailenko Chaves Magri, Adriana Lopes Motta, Marina Farrel Côrtes, Ana Carolina Mamana, Marjorie Vieira Batista, Daniel Valério da Silva Moreira, Ana Paula Croce, Mauro Cintra Giudice, André Nathan Costa, Sergio Eduardo Demarzo, Alexandra Gomes dos Santos, Thais Guimarães, Vera Lucia Teixeira de Freitas, Sílvia Figueiredo Costa, Maria Aparecida Shikanai Yasuda   +18 more
wiley   +1 more source

Selection and Characterisation of Minor Histocompatibility Antigen‐Specific Regulatory T Cells in Fully HLA‐Matched Setting for GVHD Therapy

European Journal of Immunology, Volume 55, Issue 12, December 2025.
We optimised a protocol for mHA‐specific Treg (mTreg) selection in an HLA‐matched context while defining its phenotype, transcriptional state and function. mTreg were highly activated and exerted specific, HLA class II‐, contact‐dependent suppression. This protocol can be explored as a highly personalised antigen‐specific Treg‐based therapy in future ...
Carolina Paulino Pacini, Rita I. Azevedo, Luís Ramalhete, Hugo A. J. Lainé, Maria V. D. Soares, João F. Lacerda   +5 more
wiley   +1 more source

Monitoring Variant Allele Fraction in VEXAS Syndrome: A Comparison of Digital PCR and Next‐Generation Sequencing

eJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Background VEXAS syndrome is an adult‐onset, X‐linked autoinflammatory disorder resulting from somatic variations in the UBA1 gene. Aim To evaluate the adequacy of the digital PCR (dPCR) to follow up the variant allele frequency (VAF) on response to the treatment in patients with VEXAS. Patient and Methods This study is a 1‐year follow‐up of a
Alba Exposito‐Bey, Marco Antonio Montes‐Cano, Salvador Payán‐Pernía, José Raúl García‐Lozano, María Francisca González‐Escribano   +4 more
wiley   +1 more source

Transfusion consent in Brazil: A nationwide survey of practices and form content

Vox Sanguinis, Volume 120, Issue 12, Page 1254-1258, December 2025.
Abstract Background and Objectives Obtaining consent for blood transfusion is a critical component of patient safety and promotes active patient engagement. This study aimed to assess how this practice is currently implemented in Brazil. Materials and Methods A cross‐sectional study was conducted from September 2024 to January 2025.
Viviane Pereira, Denise Brunetta, Rosana Cipolotti   +2 more
wiley   +1 more source

Identification of two epitypes of IGHV unmutated chronic lymphocytic leukemia with distinct B‐cell‐related epigenetic imprinting and genetic alterations

HemaSphere, Volume 10, Issue 1, January 2026.
Stella Charalampopoulou, Silvia Ramos‐Campoy, Marti Duran‐Ferrer, Anna Puiggros, Joanna Kamaso, Florence Nguyen‐Khac, Gian Matteo Rigolin, Antonio Cuneo, Rosa Collado, Rocío García‐Serra, Claudia Haferlach, Margarita Ortega, Pau Abrisqueta, Francesc Bosch, Thorsten Zenz, María Laura Blanco, Rocío Salgado, Mª Dolores García‐Malo, Eva Gimeno, Armando Lopez‐Guillermo, Elias Campo, Laurence Etter, Jacqueline Schoumans, Blanca Espinet, Jose I. Martin‐Subero   +24 more
wiley   +1 more source

Atrofia hemifacial progresiva o Síndrome Parry Romberg asociado a inmunodeficiencia

Revista Cubana de Hematología, Inmunología y Hemoterapia
La Atrofia Hemifacial Progresiva (AHP) o Síndrome Parry Romberg, es una enfermedad degenerativa rara, caracterizada por una lenta y progresiva atrofia facial unilateral que afecta al tejido celular subcutáneo, cartílago, tejido graso y estructuras óseas ...
Miriam de la C Sánchez Segura, Vianed Marsán Suárez, Consuelo Macías Abraham, Alina García García, Julio Valcárcel Llerandi, Lázaro O del Valle Pérez, Socarrás Ferrer, Ada A Arce Hernández   +7 more
doaj