Results 21 to 30 of about 10,593 (209)

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva   +7 more
wiley   +1 more source

Hemograma de cães submetidos ao envenenamento experimental por Tityus serrulatus Canine blood profile after experimental envenomation by Tityus serrulatus

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2009
Avaliou-se o hemograma de 12 cães adultos, saudáveis (14,2±5,4kg) após a inoculação de veneno do escorpião amarelo (Tityus serrulatus). Os animais foram distribuídos em dois grupos (G), com seis em cada: os do GI foram usados como controle e receberam 0 ...
E.L. Ribeiro   +6 more
doaj   +1 more source

Neurological Peculiarities of POEMS Syndrome: Experience From a Brazilian University Center

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Aim Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes (POEMS) syndrome is a rare paraneoplastic syndrome associated with significant neurologic morbidity. Better understanding of the manifestations of this disease is crucial to early diagnosis and improvement of prognosis.
Renan Fabri Rosenstein   +5 more
wiley   +1 more source

Avaliação hematológica, bioquimica e ultrassonográfica hepato-renal de caninos submetidos à terapia com Tiocolchicosídeos

open access: yesPubvet, 2018
O tiocolchicosídeo que é um derivado sulfuroso de um glicósido natural de colchicina, utilizado com miorrelaxante por ter ação menos sedativa do que outros relaxantes musculares que atuam sobre o SNC.. Esse medicamento é comumente utilizado no tratamento
Lianna Fernandes Carvalho   +7 more
doaj   +1 more source

Safety and Efficacy of Damoctocog Alfa Pegol in Previously Treated Children Aged 7 to < 12 Years With Severe Haemophilia A in the Phase 3, Open Label Alfa‐PROTECT Main Study

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background In the earlier PROTECT VIII Kids study (NCT01775618), damoctocog alfa pegol was efficacious for prevention and treatment of bleeds in children aged < 12 years with severe haemophilia A. Objective Assess the safety of damoctocog alfa pegol, including hypersensitivity and loss of efficacy (LoE) due to an immune response to ...
Margareth C. Ozelo   +13 more
wiley   +1 more source

Fatores etários no leucograma de fêmeas zebuínas sadias da raça Nelore (Bos indicus) Influence of age on the leukogram values for healthy Nelore (Zebu) cattle

open access: yesCiência Rural, 2000
Para avaliar-se a influência dos fatores etários sobre o leucograma de fêmeas zebuínas da raça Nelore, examinaram-se amostras de sangue de 158 animais, distribuídos por sete grupos etários ( até 3 meses; 3 a 6 meses; 6 a 12 meses; 12 a 24 meses; 24 a 48 ...
Joselito Nunes Costa   +5 more
doaj   +1 more source

Zika virus surveillance post‐epidemic in blood donors from São Paulo, Brazil 2016–2020

open access: yesTransfusion Medicine, EarlyView.
Abstract Introduction Zika virus (ZIKV) is primarily transmitted through the bite of the Aedes aegypti mosquito, though transmission via blood transfusion has also been documented. During the 2015 ZIKV epidemic in Brazil, severe complications were observed in pregnant women, leading to fetal microcephaly. This study evaluated the persistence of ZIKV in
Suzete Cleusa Ferreira   +12 more
wiley   +1 more source

Hematological profile of captive bearded capuchin monkeys (Sapajus libidinosus) from Northeastern Brazil

open access: yesCiência Rural, 2018
: Bearded Capuchin or Black-striped Capuchin monkeys (Sapajus lidibinosus) are New World robust capuchin monkeys widely used in medical research.
Adriano Fernandes Ferreira   +6 more
doaj   +1 more source

Dengue, chikungunya and Zika virus surveillance in blood donors in Brazil, 2019–2021

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Arbovirus infections are a major public health concern in Brazil and an ongoing blood safety concern. Periodic outbreaks of such infections are common in the general population. This study aimed to establish the rates of dengue, chikungunya and Zika virus (DENV, CHIKV, ZIKV) RNAemia among blood donors at six public ...
Eduard Grebe   +18 more
wiley   +1 more source

Iptacopan for Immune Thrombocytopenia and Cold Agglutinin Disease: A Global Phase 2 Basket Clinical Trial

open access: yesAmerican Journal of Hematology, Volume 101, Issue 2, Page 242-254, February 2026.
ABSTRACT Iptacopan is a first‐in‐class, oral, selective inhibitor of complement factor B that has demonstrated positive efficacy across several complement‐driven diseases. Here we evaluate the efficacy and safety of iptacopan monotherapy in adult patients with primary immune thrombocytopenia (ITP) and primary cold agglutinin disease (CAD). We performed
Alexander Röth   +13 more
wiley   +1 more source

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