Results 51 to 60 of about 14,988 (213)
B cell lymphoma‐derived EVs are intrinsically neutral or suppressive with respect to NK cell activity (panel 1). In the context of rituximab treatment, NK cytotoxicity is enhanced by antibody‐dependent cell‐mediated cytotoxicity (panel 2). Herein we show that, in addition, rituximab recognition of EV‐associated CD20 generates immune complexes that ...
Adrián V. Otero +19 more
wiley +1 more source
Guidelines On The Treatment Of Acute Myeloid Leukemia: Associação Brasileira De Hematologia, Hemoterapia E Terapia Celular [PDF]
381587
Teresa Cristina; Chauffaille +7 more
core
PB1910: CHRONIC MYELOID LEUKEMIA AND RELATIONSHIP TO SECONDARY SOLID NEOPLASMS
M. J. Ramos +12 more
doaj +1 more source
Regional Standardization of CLL Management: Results of a Delphi Consensus Process
ABSTRACT The therapeutic landscape of chronic lymphocytic leukemia (CLL) has been profoundly transformed by the introduction of Bruton tyrosine kinase and BCL‐2 inhibitors. Despite improved survival outcomes, treatment selection remains complex, particularly in older patients with comorbidities, frailty, and increased infectious vulnerability.
Enrica Antonia Martino +22 more
wiley +1 more source
ABSTRACT In a large multicenter real‐world cohort, we aimed to evaluate outcomes of FLAG‐Ida salvage therapy for relapsed/refractory (R/R) acute myeloid leukemia (AML) and validated the SALFLAGE prognostic score. We analyzed 1079 adults with R/R AML treated across 112 PETHEMA institutions over 26 years (1998–2024), including patients with primary ...
Gaspar Aspas Requena +49 more
wiley +1 more source
Multiple myeloma: A tale of deregulated transcription factors
Abstract A comprehensive understanding of the molecular mechanisms underlying multiple myeloma (MM) pathogenesis is essential for developing therapeutic strategies that overcome disease heterogeneity and treatment relapse. In this review, we focus on transcription factors (TFs), key regulators of gene expression that play critical roles in normal ...
Nahia Gómez‐Echarte +5 more
wiley +1 more source
Síndromes mielodisplásicas: a histopatologia como fator prognóstico
Bone marrow biopsy allows evaluation of cellularity, abnormal localization of immature precursors and fibrosis in myelodysplastic syndrome. It has been considered important to make diagnosis and prognosis of this disorder.
Romeo, Maura [UNIFESP] +7 more
core +1 more source
Abstract Paroxysmal nocturnal hemoglobinuria (PNH) is an ultra‐orphan disease. In 2026, approved complement inhibitors (CIs) for PNH include three C5 inhibitors (C5i) and three proximal inhibitors (PIs). Clinical trials for the approved PI pegcetacoplan, iptacopan, and C5i + danicopan had clear protocols for changing from terminal to PI, extrapolated ...
Morag Griffin +15 more
wiley +1 more source
ANÁLISE SOROLÓGICA DOS DOADORES DE SANGUE DE UM HEMOCENTRO REFERÊNCIA DO ESTADO DO NORDESTE
Introdução: Os hemocomponentes e hemoderivados são originados da doação de sangue por um doador. Toda doação de sangue deve ser altruísta, voluntária e não gratificada.
JIOD Santos +9 more
doaj +1 more source

