Results 211 to 220 of about 376,968 (292)

Impact of prior solid tumor on outcomes of hematopoietic stem cell transplantation for hematologic malignancies: a propensity score-matched study. [PDF]

Front Immunol
Luo J, Wang M, Zhou Y, Wang W, Cao W, Zhang R, Chen X, Ma Q, Wei J, Zhai W, He Y, Yang D, Pang A, Feng S, Han M, Jiang E.   +15 more
europepmc   +1 more source

Incidence, Risk Factors, and Outcomes of Chronic Graft-versus-Host Disease in Pediatric Patients with Hematologic Malignancies after T Cell-Replete Myeloablative Haploidentical Hematopoietic Stem Cell Transplantation with Antithymocyte Globulin/Granulocyte Colony-Stimulating Factor

, 2020
Feifei Tang, Yifei Cheng, Lan‐Ping Xu, Xiaohui Zhang, Chen‐Hua Yan, Wei Han, Yu‐Hong Chen, Xiao‐Jun Huang, Yu Wang   +8 more
openalex   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

Advanced Science, EarlyView.
Fibroblast activation protein alpha‐positive (FAPα+) macrophages, a distinct subset of multiple myeloma (MM)‐associated macrophages, drive immune evasion in MM through multi‐faceted mechanisms. FAPα physically interacts with vimentin (VIM) and triggers its phosphorylation at the S72 residue, which in turn induces PD‐L1 transcription. Additionally, FAPα
Huiyao Gu, Zhenfeng Dai, Xi Huang, Enfan Zhang, Xinyuan Dai, Haoguang Chen, Wen Cao, Jinna Zhang, Yifan Hou, Haimeng Yan, Yang Yang, Li Yang, Yi Li, Wenlong Lin, Zhen Cai, Jingsong He   +15 more
wiley   +1 more source

Eculizumab inhibits thrombotic microangiopathy and improves renal function in pediatric patients with atypical hemolytic uremic syndrome [PDF]

, 2013
Al-Akash, Samhar I, Ardissimo, Gianluigi, Bedrosian, Camille L, Evans, Jonathan, Fila, Marc, Greenbaum, Larry, Henning, Paul, Licht, Christoph, Lieberman, Kenneth V, Maringhini, Silvio, Ogawa, Masayo, Pape, Lars, Rees, Lesley, Tsimaratos, Michel, Van De Kar, Nicole, Vande Walle, Johan   +15 more
core  

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Evacuation of axillary hematoma causing brachial plexus compression in newly diagnosed leukemia: a case report and literature review. [PDF]

Case Reports Plast Surg Hand Surg
Mordukhovich I, Sulaiman HO, Frisbie S, Tufaro A, Bassiri Gharb B, Rampazzo A.   +5 more
europepmc   +1 more source

Hemostatic and hematological profiles of horses with natural occurrence large colon impaction and medically treated

, 2016
Edmilson Rodrigo Daneze, Deborah Penteado Martins Dias, Gabriela Bueno, José Corrêa de Lacerda Neto, Áureo Evangelista Santana, Antônio Sérgio Ferraudo, Márcia Ferreira da Rosa Sobreira   +6 more
openalex   +2 more sources

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Bone Marrow-Sparing Pelvic Radiotherapy: Clinical Evidence, Dosimetric Constraints, and Clinical Outcomes. [PDF]

Cureus
El Mjabber R, Alami R, Naim A, Kouhen F, Ismaili N, El Majjaoui S, Dahbi Z.   +6 more
europepmc   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source